Genetic variation in testicular development in mice of the C57BL/10ScSn, C57BL/6By and BALB/cBy strains and the CXB recombinant-inbred lines.
Genetic variation in testicular development in mice of the C57BL/10ScSn, C57BL/6By and BALB/cBy strains and the CXB recombinant-inbred lines.
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C57BL/10ScSn、C57BL/6By 和 BALB/cBy 品系以及 CXB 重组近交系小鼠睾丸发育的遗传变异。
DOI：
10.1530/jrf.0.0870587
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
J. Shire
中科院分区：
文献类型：
--
作者：
N. M. Shukri;J. Shire
与C57 BL/6By小鼠相比，BALB/cBy小鼠的睾丸在60日龄时重41%，曲细精管在120日龄时横截面积大41%。在C57BL/6By或C57BL/10ScSn小鼠中，睾丸绝对重量在60至120日龄之间没有增加，但在BALB小鼠中却增加了，与生精小管大小的变化平行。在来自BALB/cBy和C57BL/6By品系杂交的所有7种CXB重组近交系（RI）小鼠品系的小鼠中，在此年龄段内发生了显著的睾丸生长。成年重组小鼠表现出广泛的表型，从睾丸明显比BALB重的小鼠到睾丸大小与C57 BL/10ScSn小鼠相同（60天）的小鼠，这意味着存在几个影响成年小鼠睾丸大小的可分离因素。在30日龄时，RI系分为两组;一组具有小睾丸，如C57BL/6By，另一组具有较大睾丸，如BALB/cBy小鼠。青春期前睾丸重量的分离模式是相同的H-2组织相容性位点。
When compared with C57BL/6By mice, BALB/cBy mice had testes that were 41% heavier at 60 days of age and seminiferous tubules that were 41% greater in cross-sectional area at 120 days. Absolute testicular weight did not increase between 60 and 120 days of age in either C57BL/6By or C57BL/10ScSn mice but did in BALB mice, paralleling changes in the size of the seminiferous tubules. Significant testicular growth took place over this age period in mice of all seven of the CXB recombinant-inbred (RI) strains of mice derived from a cross of the BALB/cBy and C57BL/6By strains. The wide range of phenotypes shown by adult recombinant mice, which ranged from those with significantly heavier testes than BALB to those with testes the same size (at 60 days) as those of C57BL/10ScSn mice, implied the existence of several separable factors affecting testicular size in adults. At 30 days of age the RI lines fell into two groups; one with small testes like C57BL/6By and the other with larger testes like BALB/cBy mice. The segregation pattern for prepubertal testicular weight was identical to that for the H-2 histocompatibility locus.
因促性腺激素诱导排卵差异而选择的小鼠品系的睾丸功能。
DOI：
10.1677/joe.0.0900367
发表时间：
1981
期刊：
The Journal of endocrinology
影响因子：
--
作者：
Wolfe,HG;Bartke,A;Amador,A;VanSickle,M;Dalterio,S;Brown,D
通讯作者：
Brown,D