Displacement of primary sensorimotor cortex activation after subcortical stroke: a longitudinal PET study with clinical correlation
Displacement of primary sensorimotor cortex activation after subcortical stroke: a longitudinal PET study with clinical correlation
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DOI：
10.1016/s1053-8119(03)00205-2
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发表时间：
2003-08-01
期刊：
影响因子：
5.7
通讯作者：
Baron, JC
中科院分区：
文献类型：
--
作者：
Calautti, C;Leroy, F;Baron, JC
5例左侧纹状体囊梗死患者在卒中后2个月左右和卒中后8个月左右分别进行了两次PET研究。在PET 1和PET 2，同病灶初级感觉运动（SM 1）激活峰Talairach坐标进行了比较，从7个年龄匹配的健康对照。在PET 1时，SM 1激活峰有显著的后移，这证实了先前的报告，可能代表运动表征的暴露/去抑制。随着时间的推移，坐标没有显著变化，从PET I到PET 2的坐标变化与伴随的运动恢复之间没有显著相关性。因此，SM 1激活峰的后移对恢复的影响仍然难以捉摸。(C)2003 Elsevier Science（美国）。All rights reserved.
Five patients with left striatocapsular infarction were studied twice with PET during auditory-cued right thumb-index tapping, around 2 months after stroke and again around 8 months after stroke. At PET1 and PET2, the ipsilesional primary sensorimotor (SM1) activation peak Talairach coordinates were compared to those from seven aged-matched healthy controls. At PET1, there was a significant posterior displacement of SM1 activation peak, which confirms a previous report and may represent unmasking/disinhibition of motor representations. Over time, there was no significant change in the coordinates, and no significant correlation between coordinate changes from PET I to PET2 and concomitant motor recovery. The implications of posterior displacement of SM1 activation peak for recovery therefore remain elusive. (C) 2003 Elsevier Science (USA). All rights reserved.