Acquired cystic disease of the kidneys: a hazard of long-term intermittent maintenance haemodialysis.
Acquired cystic disease of the kidneys: a hazard of long-term intermittent maintenance haemodialysis.
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获得性肾脏囊性疾病：长期间歇性维持性血液透析的危险。
DOI：
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发表时间：
1977
影响因子：
3.4
通讯作者：
D. Oliver
中科院分区：
文献类型：
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作者：
M. Dunnill;P. Millard;D. Oliver
1968-76年间，对30例长期间歇性维持性血液透析患者进行了尸检。其中14例发展为双侧肾脏囊性病变。这些患者第一次出现时的临床、病理和放射学检查没有发现任何肾囊性改变的证据。这种情况的主要并发症是出血和肿瘤形成。6例患者发生肾肿瘤，其中5例为多发性。这些肿瘤的组织学外观并没有表明它们是否会表现出侵袭性。1例死于原发于肾脏的转移性癌。如果维持性血液透析患者反复出现血尿或发现肾脏增大，应怀疑是获得性肾囊性疾病。
In the period 1968-76, necropsies were carried out on 30 patients who had been treated by long-term intermittent maintenance haemodialysis. Fourteen of these patients developed bilateral cystic disease of the kidney. Clinical, pathological, and radiological investigation of these patients when they first presented did not reveal any evidence of renal cystic change. The main complications of this condition are haemorrhage and tumour formation. Six patients developed renal tumours, and in five cases these were multiple. The histological appearance of these neoplasms gave no indication as to whether they would behave in an aggressive manner. One patient died of metastatic carcinomatosis from a renal primary. The condition of acquired cystic disease of the kidney should be suspected if patients on maintenance haemodialysis suffer from recurrent haematuria or are found to have enlarging kidneys.