Piperine and Its Role in Chronic Diseases
Piperine and Its Role in Chronic Diseases
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DOI：
10.1007/978-3-319-41334-1_8
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发表时间：
2016-01-01
期刊：
影响因子：
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通讯作者：
Sahebkar, Amirhossein
中科院分区：
文献类型：
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作者：
Derosa, Giuseppe;Maffioli, Pamela;Sahebkar, Amirhossein
生物碱包括天然存在的化合物家族，其主要含有碱性氮原子。黑胡椒碱是一种存在于黑胡椒（Piper nigrum）（最广泛使用的香料之一）、长胡椒（Piper longum）和属于胡椒科的其他胡椒属果实中的生物碱。黑胡椒碱是黑胡椒独特的咬味品质的原因。胡萝卜碱具有许多药理作用和几种健康益处，特别是对慢性疾病，如降低胰岛素抵抗，抗炎作用和改善肝脂肪变性。本章的目的是总结胡椒碱的影响，单独或与其他药物和植物化学物质相结合，在慢性疾病。
Alkaloids include a family of naturally occurring chemical compounds containing mostly basic nitrogen atoms. Piperine is an alkaloid present in black pepper (Piper nigrum), one of the most widely used spices, in long pepper (Piper longum), and other Piper species fruits belonging to the family of Piperaceae. Piperine is responsible for the black pepper distinct biting quality. Piperine has many pharmacological effects and several health benefits, especially against chronic diseases, such as reduction of insulin-resistance, anti-inflammatory effects, and improvement of hepatic steatosis. The aim of this chapter is to summarize the effects of piperine, alone or in combination with other drugs and phytochemicals, in chronic diseases.