Great Lakes Biorepository Research Network's Annual Biobanking Symposium: A Focus on Precision Medicine.

Great Lakes Biorepository Research Network's Annual Biobanking Symposium: A Focus on Precision Medicine.
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五大湖生物样本库研究网络年度生物样本库研讨会:聚焦精准医学。

DOI:
10.1089/bio.2019.0022
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发表时间:
2019
影响因子:
1.6
通讯作者:
Jewell,ScottD
Jewell,ScottD
中科院分区:
生物学4区
文献类型:
--
作者:
Paulauskis,JosephD;Blanc,VictoriaM;Carey,Thomas;Chesla,DavidW;Frey,RenéeC;Geddes,Timothy;Keats,Jonathan;Loup,Allan;Pruetz,Barbara;Rohrer,DanielC;Valley,DanaR;Tomlinson,Tom;Akervall,Jan;Wilson,GeorgeD;Jewell,ScottD

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(GLBRN)年度科学研讨会,举办的目的是促进合作和研究机会以及生物样本库专业知识和经验的分享。密歇根大学 (UM) 和密歇根大学医学院中央生物样本库主办了 2018 年研讨会,主题为“精准医学时代的生物样本收集和生物样本库”。主要来自GLBRN主办机构的100余名注册人员参加了会议。会议的形式包括两位主讲人,Jonathan Keats 博士和 Dave Chesla,BSc、MHA、PAASCP、AAPA、HT,他们分别就多发性骨髓瘤遗传学和“我们所有人”倡议的主题进行了发言。随后举办了四场研讨会,主题分别为生物样本库、肿瘤组织采购、知情同意和质量管理的关键要素。本报告提供了研讨会的亮点和主要学习信息。 GLBRN 始于 2013 年 11 月威廉·博蒙特年度生物库研讨会期间的四家密歇根机构(威廉·博蒙特卫生系统、范安德尔研究所 (VARI)、密歇根大学和密歇根州立大学)。最近,安娜堡的圣约瑟夫·梅西健康中心作为第五个机构成员加入(图 1)。GLBRN 的基本原理是改善研究人员的合作机会,专注于改善生物库相关科学、可持续性和质量的质量保证/质量控制。 GLBRN 是一个自愿参与的组织,在没有外部资金的情况下有机发展,并渴望成为一个互动和高效的网络,通过与参与机构合作提供促进研究人员驱动的研究以及加强生物样本库管理的机会。基于谅解备忘录/UBMTA 的机构协议,旨在最大限度地减少向成员机构的研究人员转移生物样本的障碍。然而,计划花更多的时间作为区域性生物样本库的资源和教育合作社,GLBRN 协议提供了优势,作为各机构签署的法律文件,以形成机构生物样本库制定的共同目标、程序和流程,同时不再是成员互动的唯一指导原则。 GLBRN 活动是一种简单的互动和贡献结构,任何机构或研究中心都可以通过同意支持一套指导原则来加入,这些原则包括 MOU/UBMTA 协议、生物样本收集知情同意的共同要素、年度信息会议、联盟电话会议以及 GLBRN 网站材料的使用和通知。
(GLBRN) annual scientific symposium, held to promote collaborations and research opportunities and the sharing of biobanking expertise and experiences. The University of Michigan (UM) and the UM Medical School Central Biorepository, promoting the theme ‘‘Biospecimen Collections and Biobanking in the Era of Precision Medicine,’’hosted the 2018 symposium. Over 100 registrants originating mainly from the GLBRN host institutions attended the meeting. The format of the meeting consisted of two keynote speakers, Jonathan Keats, PhD, and Dave Chesla, BSc, MHA, PAASCP, AAPA, HT, who spoke on the topics of multiple myeloma genetics and the ‘‘All of Us’’initiative, respectively. This was followed by four workshops centered on the Key Elements of Biobanking, Oncologic Tissue Procurement, Informed Consent, and Quality Management. This report provides highlights and key learning messages of the symposium. The GLBRN began with four Michigan institutions (William Beaumont Health System, Van Andel Research Institute (VARI), UM, and Michigan State University in November 2013 during the William Beaumont’s Annual Biobank Symposium. Recently St. Joseph Mercy Health, Ann Arbor, joined as the fifth institutional member (Fig. 1). The rationale for the GLBRN was to improve collaboration opportunities for researchers, focus on improved quality assurance/quality control for biobank-related science, sustainability, and to develop an active interaction among peer biobanking groups. The GLBRN is a voluntary engagement to build a ‘‘grass root’’-based organization. The organization grew organically, without external funding, and aspired to be an interactive and efficient network. One goal was to improve research by collaborating with participating institutions to provide human samples that would promote investigatordriven research as well as an opportunity to enhance management of the biobanks. The encouragement to distribute stored biospecimens is ongoing and offers the opportunity using a MOU/UBMTA-based institutional agreement to minimize barriers for the transfer of biospecimens to researchers from member institutions. However, plans to spend more time as like-minded biobankers as a resource and educational cooperative for biorepositories on a regional effort are now the primary focus of the GLBRN. The GLBRN agreement provides advantages, as a legal document signed by the respective institutions to forge common goals, procedures, and processes developed by the institutions’ biobanks, while no longer being the sole guiding principle for the members to interact. The GLBRN activity is a simple structure of interaction and contribution that any institute or research center can join by agreeing to support the set of guiding principles. Principles include the MOU/UBMTA agreement, common elements of informed consent for the collection of biospecimens, an annual informational meeting, consortium conference calls, and use and notification of materials from the GLBRN website.
多发性骨髓瘤中新型融合转录本的鉴定
DOI: 10.1136/jclinpath-2017-204961
发表时间: 2018
影响因子: 3.4
作者:
Mingxuan Lin;Peak;L. Chiu;C. Chua;K. Ban;A. Lin;Zit;Tae;B. Yan;W. Chng
通讯作者: W. Chng