The puff-specific Drosophila protein Bj6, encoded by the gene no-on transient A, shows homology to RNA-binding proteins

The puff-specific Drosophila protein Bj6, encoded by the gene no-on transient A, shows homology to RNA-binding proteins
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由基因 no-ontransient A 编码的泡芙特异性果蝇蛋白 Bj6 与 RNA 结合蛋白具有同源性

DOI:
10.1007/bf00337601
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发表时间:
1990
期刊:
影响因子:
1.6
通讯作者:
H. Saumweber
H. Saumweber
中科院分区:
生物学3区
文献类型:
--
作者:
H. Besser;P. Schnabel;C. Wieland;Elke Fritz;R. Stanewsky;H. Saumweber

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通过表达克隆的方法,获得了泡芙特异蛋白Bj6的编码DNA。该基因定位于X染色体上的14c1、2中,在胚胎发育过程中普遍表达,在胚胎发育的前12h有显著表达。基因克隆和基因组克隆已经测序,显示出一个2.1kb的单一开放阅读框架,编码一个Mr=77000的碱性蛋白。在蛋白质的氨基末端,我们检测到一段重复的氨基酸,中心是一个与RNA结合蛋白同源的区域,包含RNA结合蛋白的RNP 1和RNP 2共同基序,而羧基末端富含带电氨基酸。Bj6蛋白是非瞬时A基因的产物,该基因是果蝇正常视力和求偶行为所必需的基因。
The DNA coding for the puff-specific protein Bj6 has been isolated by expression cloning. The gene is localized in 14C1,2 on the X chromosome and is expressed ubiquitously during embryonic development with prominent expression during the first 12 h of embryogenesis. cDNA and genomic clones have been sequenced and show a single open-reading frame of 2.1 kb length, coding for a Mr=77000 basic protein. In the aminoterminal half of the protein we detect stretches of repeated amino acids, centrally a region with homology to RNA-binding proteins containing the RNP 1 and RNP 2 consensus motif of RNA binding proteins, and the carboxyterminal part is rich in charged amino acids. The Bj6 protein is a product of the gene no-on transient A, a gene required for normal vision and courtship behaviour in Drosophila.
DOI: 10.1073/pnas.80.5.1194
发表时间: 1983-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
YOUNG, RA;DAVIS, RW
通讯作者: DAVIS, RW
果蝇求爱歌曲的不和谐突变体:分离、行为和细胞遗传学。
DOI: 10.1093/genetics/118.2.267
发表时间: 1988
期刊: Genetics
影响因子: 3.3
作者:
Kulkarni,SJ;Steinlauf,AF;Hall,JC
通讯作者: Hall,JC
DOI: 10.1073/pnas.79.14.4381
发表时间: 1982-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
LANGERSAFER, PR;LEVINE, M;WARD, DC
通讯作者: WARD, DC