EFFECT OF CONTRALATERAL SOUND STIMULATION ON THE DISTORTION-PRODUCT 2F(1)-F(2) IN HUMANS - EVIDENCE OF A FREQUENCY SPECIFICITY
EFFECT OF CONTRALATERAL SOUND STIMULATION ON THE DISTORTION-PRODUCT 2F(1)-F(2) IN HUMANS - EVIDENCE OF A FREQUENCY SPECIFICITY
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DOI：
10.1016/0378-5955(93)90064-8
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发表时间：
1993-06-01
期刊：
影响因子：
2.8
通讯作者：
COLLET, L
中科院分区：
文献类型：
--
作者：
CHERYCROZE, S;MOULIN, A;COLLET, L
本文研究了39名听力正常人在63次对侧刺激下三次2f 1-f2畸变产物（DPOAE）的抑制频率特性。每个阶段包括暴露于五个连续系列的随机对侧NBN频率，中心频率在0.25和8 kHz之间，同时测量设置在四个研究频率之一的2f 1-f2，即，1、2、3或5 kHz。对于2f 1-f2的每个值，使用方差分析和学生t检验，以指示并在必要时定位可能的显著频率特异性。结果表明，对侧声刺激对2f 1-f2 DPOAE的抑制具有频率特异性，至少对1和2kHz的中频有抑制作用。当2f 1-f2 = 1 kHz时，对侧NBN中心频率在1 kHz左右时，频率特异性特别显著。当2f 1-f2 = 2kHz时，引起显著抑制效果的中心频率包括2kHz附近的频率以及1 kHz附近的较低频率。这些观察结果支持了DPOAE的抑制是由内侧橄榄-耳蜗传出系统介导的解释。
The frequency characteristics of the suppression by contralateral stimulations, of the cubic 2f1-f2 distortion products (DPOAEs), were studied during 63 sessions performed in 39 humans with normal hearing. Each session consisted of exposure to five successive series of randomized contralateral NBN frequencies centered between 0.25 and 8 kHz, while measuring 2f1-f2 set at one of the four studied frequencies, i.e., 1, 2, 3 or 5 kHz. For each value of 2f1-f2, analysis of variance and Student's t-test were used in order to indicate and, if necessary, to localize, a possible significant frequency specificity. Results showed that the suppression exerted on 2f1-f2 DPOAEs by contralateral sound stimulation, is frequency specific, at least for middle frequencies of 1 and 2 kHz. The frequency specificity is specially marked when 2f1-f2 = 1 kHz with contralateral NBN central frequencies around 1 kHz. When 2f1-f2 = 2 kHz, central frequencies which induced a significant suppressive effect include frequencies around 2 kHz and also lower frequencies around 1 kHz. These observations support the interpretation that the suppression of the DPOAE is mediated by the medial olivo-cochlear efferent system.