Doc2Hpo: a web application for efficient and accurate HPO concept curation
Doc2Hpo: a web application for efficient and accurate HPO concept curation
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DOI：
10.1093/nar/gkz386
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发表时间：
2019-07-02
影响因子：
14.9
通讯作者：
Weng, Chunhua
中科院分区：
文献类型：
--
作者：
Liu, Cong;Kury, Fabricio Sampaio Peres;Weng, Chunhua
我们推出了 Doc2Hpo，这是一个交互式 Web 应用程序，它可以使用人类表型本体 (HPO) 通过自动概念标准化从临床文本中进行交互式且高效的表型概念管理。用户可以实时编辑Doc2Hpo自动提取的HPO概念，并将提取的HPO概念导出到基因优先级工具中。我们的评估表明，Doc2Hpo 显着减少了人工工作量，同时在 HPO 概念管理中实现了高精度。 Doc2Hpo 可在 https://impact2.dbmi.columbia 免费获取。 edu/doc2hpo/.源代码可在 https://github.com/stormliucong/doc2hpo 获取，用于本地安装以保护健康数据。
We present Doc2Hpo, an interactive web application that enables interactive and efficient phenotype concept curation from clinical text with automated concept normalization using the Human Phenotype Ontology (HPO). Users can edit the HPO concepts automatically extracted by Doc2Hpo in real time, and export the extracted HPO concepts into gene prioritization tools. Our evaluation showed that Doc2Hpo significantly reduced manual effort while achieving high accuracy in HPO concept curation. Doc2Hpo is freely available at https://impact2.dbmi.columbia. edu/doc2hpo/. The source code is available at https://github.com/stormliucong/doc2hpo for local installation for protected health data.