Indocyanine green angiographic findings in nonproliferative diabetic retinopathy
Indocyanine green angiographic findings in nonproliferative diabetic retinopathy
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DOI：
10.1016/s0002-9394(98)00148-2
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发表时间：
1998-08-01
影响因子：
4.2
通讯作者：
Yassur, Y
中科院分区：
文献类型：
--
作者：
Weinberger, D;Kramer, M;Yassur, Y
目的：报道非增殖型糖尿病视网膜病变患者的吲哚青绿血管造影表现。方法：对42例(42只眼)非增殖型糖尿病视网膜病变患者在荧光素血管造影的基础上进行吲哚青绿血管造影检查。结果：42只眼中，5只眼(12%)在吲哚青绿血管造影术中表现为晚期小叶斑点状强荧光区和低荧光区(“盐和胡椒”样)。20只眼(48%)在吲哚青绿血管造影术上表现为弥漫性晚期强荧光，与荧光素血管造影术上视网膜毛细血管无灌注区和视网膜水肿相对应。3564个微动脉瘤分为三种类型：58个(1.6%)在荧光素血管造影上主要出现，在吲哚青绿血管造影上很微弱，3029个(85%)在荧光素血管造影和吲哚青绿血管造影上出现，477个(13.4%)在吲哚青绿血管造影上表现为独特的高荧光。由于成像的局限性，这些血管造影改变在荧光素血管造影术中没有观察到。吲哚青绿血管造影术在评估非增殖性糖尿病视网膜病变的脉络膜视网膜血管改变方面可能是荧光素血管造影术的有用辅助手段。《眼科杂志》1998；126：238-241。(C)1998，Elsevier Science Inc.版权所有。)
PURPOSE: To report angiographic findings of nonproliferative diabetic retinopathy patients by means of indocyanine green angiography.METHODS: Forty two eyes (42 patients) with nonproliferative diabetic retinopathy were evaluated by indocyanine green angiography in addition to fluorescein angiography. Angiographic findings with the two imaging techniques were compared with the red-free fundus appearance.RESULTS: Among the 42 eyes, five (12%) had the appearance on indocyanine green angiography of lobular spotty hyperfluorescent and hypofluorescent areas ("salt and pepper" appearance) in the very late phase. Twenty eyes (48%) presented with diffuse late-phase hyperfluorescence on indocyanine green angiography, corresponding to areas of retinal capillary nonperfusion on fluorescein angiography, and retinal edema. A total of 3,564 microaneurysms were divided into three types: 58 (1.6%) appeared mainly on the fluorescein angiography and very faintly on the indocyanine green angiography, 3,029 (85%) appeared on the fluorescein angiography and the indocyanine green angiography, and 477 (13.4%) were uniquely hyperfluorescent on the indocyanine green angiography.CONCLUSIONS: Lndocyanine green angiography in patients with nonproliferative diabetic retinopathy disclosed microvascular findings that were in addition to those shown on fluorescein angiography. These angiographic changes were not ob served on fluorescein angiography because of im aging limitations. Indocyanine green angiography may be a useful adjunct to fluorescein angiography in the evaluation of chorioretinal vascular changes in nonproliferative diabetic retinopathy. (Am J Ophthalmol 1998;126:238-241. (C) 1998 by Elsevier Science Inc. All rights reserved.).