PhyloFacts:: an online structural phylogenomic encyclopedia for protein functional and structural classification
PhyloFacts:: an online structural phylogenomic encyclopedia for protein functional and structural classification
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DOI：
10.1186/gb-2006-7-9-r83
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发表时间：
2006-01-01
期刊：
影响因子：
12.3
通讯作者：
Sjolander, Kimmen
中科院分区：
文献类型：
--
作者：
Krishnamurthy, Nandini;Brown, Duncan P.;Sjolander, Kimmen
伯克利系统基因组学小组提出了PhyloFacts，这是一个结构系统基因组百科全书，包含近10,000本蛋白质家族和结构域的“书籍”，具有预先计算的结构，功能和进化分析。通过在进化框架中整合各种实验数据和生物信息学方法，PhyloFacts使生物学家能够避免与功能同源预测相关的系统误差。用户可以提交序列分类到家族和功能亚家族。PhyloFacts是一个全球性的网络资源，可从http://phylogenomics.berkeley.edu/phylofacts获得。
The Berkeley Phylogenomics Group presents PhyloFacts, a structural phylogenomic encyclopedia containing almost 10,000 'books' for protein families and domains, with pre-calculated structural, functional and evolutionary analyses. PhyloFacts enables biologists to avoid the systematic errors associated with function prediction by homology through the integration of a variety of experimental data and bioinformatics methods in an evolutionary framework. Users can submit sequences for classification to families and functional subfamilies. PhyloFacts is available as a worldwide web resource from http://phylogenomics.berkeley.edu/phylofacts.