Effect of age on long-term heart rate variability
Effect of age on long-term heart rate variability
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DOI：
10.1016/s0008-6363(97)00107-7
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发表时间：
1997-07-01
影响因子：
10.8
通讯作者：
Igel, G
中科院分区：
文献类型：
--
作者：
Yeragani, VK;Sobolewski, E;Igel, G
目的：先前对心率短期时间序列的研究表明，年龄与不同频段心率变异性的频谱功率之间存在反比关系。在这项研究中，我们研究了年龄（6-61 岁）与长期心率变异性之间的关系。方法：我们获得了 33 名健康受试者（11 名儿童和 22 名成人）的 24 小时动态心电图。通过使用频谱分析和时间序列的分形维数来分析心率数据。结果：我们发现，在清醒和睡眠期间，年龄与极低频（VLF，0.0033-0.04 Hz）、低频（LF，0.04-0.15 Hz）和高频（HF，0.15-0.5 Hz）功率和分形维数之间存在显着负相关，而年龄与 LF/HF 比率之间存在显着正相关。年龄和超低频（ULF，< 0.0033 Hz）仅在清醒期间呈适度负相关。结论：睡眠 ULF 功率不受年龄的显着影响，而 VLF、LF 和 HF 功率以及心率分形维数在清醒和睡眠期间随年龄显着降低。 (C) 1997 Elsevier Science B.V.
Objective: Previous studies on short-term time series of heart rate suggest an inverse relationship between age and spectral powers of heart rate variability in various frequency bands. In this study, we examined the relationship between age (6-61 years) and long-term heart rate variability. Methods: We obtained 24-h Holter ECG in 33 healthy human subjects (11 children and 22 adults). The heart rate data were analyzed by using spectral analysis and fractal dimensions of the time series. Results: We found a significant negative correlation between age and very low frequency (VLF, 0.0033-0.04 Hz), low frequency (LF, 0.04-0.15 Hz) and high frequency (HF, 0.15-0.5 Hz) powers and fractal dimensions during awake as well as sleep periods, and a positive correlation between age and LF/HF ratios. Age and ultra-low frequency (ULF, < 0.0033 Hz) were modestly and negatively correlated only during the awake period. Conclusions: Sleep ULF power is not significantly affected by age, whereas VLF, LF and HF powers and fractal dimensions of heart rate significantly decrease with age during awake as well as sleep periods. (C) 1997 Elsevier Science B.V.