Proteome Analysis Database: online application of InterPro and CluSTr for the functional classification of proteins in whole genomes
Proteome Analysis Database: online application of InterPro and CluSTr for the functional classification of proteins in whole genomes
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DOI：
10.1093/nar/29.1.44
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发表时间：
2001-01-01
影响因子：
14.9
通讯作者：
Zdobnov, E
中科院分区：
文献类型：
--
作者：
Apweiler, R;Biswas, W;Zdobnov, E
EBI的SWISS-PROT小组利用现有资源开发了蛋白质组分析数据库，并提供了细菌、古细菌和真核生物完整基因组的预测蛋白质编码序列的比较分析（http：//www.ebi.ac.uk/proteome/）。所使用的两个主要项目InterPro和CluSTr为家族、结构域和位点提供了新的视角，并涵盖了每个完整基因组中31-67%的蛋白质（InterPro统计）。CluSTr涵盖了三个完整的真核生物基因组和不完整的人类基因组数据。蛋白质组分析数据库附带一个程序，该程序被设计用于对数据库中的任何一个蛋白质组与任何其他一个或多个蛋白质组进行InterPro蛋白质组比较。
The SWISS-PROT group at EBI has developed the Proteome Analysis Database utilising existing resources and providing comparative analysis of the predicted protein coding sequences of the complete genomes of bacteria, archaea and eukaryotes (http:// www.ebi.ac.uk/proteome/). The two main projects used, InterPro and CluSTr, give a new perspective on families, domains and sites and cover 31-67% (InterPro statistics) of the proteins from each of the complete genomes. CluSTr covers the three complete eukaryotic genomes and the incomplete human genome data. The Proteome Analysis Database is accompanied by a program that has been designed to carry out InterPro proteome comparisons for any one proteome against any other one or more of the proteomes in the database.