Recommended reading in population pharmacokinetic pharmacodynamics.

Recommended reading in population pharmacokinetic pharmacodynamics.
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DOI:
10.1208/aapsj070237
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发表时间:
2005-10-05
期刊:
The AAPS journal
影响因子:
--
通讯作者:
Bonate, Peter L
Bonate, Peter L
中科院分区:
其他
文献类型:
--
作者:
Bonate, Peter L

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开发技能或专业知识,以创建有用的人口药代动力学-药效学模型可能是一项艰巨的任务,数学和统计的复杂性水平是这样的,新手到该领域往往是不堪重负。学习这个领域的一个好的开始是阅读文献中的文章。然而,涉及群体药代动力学药效学的文章数量每年呈指数级增长,因此选择阅读哪些文章可能很困难。这篇评论的目的是为该领域的新手提供一个推荐的阅读清单。该列表的选择是基于文章在该领域的影响力,文章的质量,或突出文章中包含的一些重要细节。在阅读列表中的文章后,相信读者将对该领域有一个广泛的概述,并为更详细的阅读文献奠定坚实的基础。
Developing the skills or expertise to create useful population pharmacokinetic-pharmacodynamic models can be a daunting task-the level of mathematical and statistical complexity is such that newcomers to the field are frequently overwhelmed. A good place to start in learning the field is to read articles in the literature. However, the number of articles dealing with population pharmacokinetic pharmacodynamics is exponentially increasing on a yearly basis, so choosing which articles to read can be difficult. The purpose of this review is to provide a recommended reading list for newcomers to the field. The list was chosen based on perceived impact of the article in the field, the quality of the article, or to highlight some important detail contained within the article. After reading the articles in the list, it is believed that the reader will have a broad overview of the field and have a sound foundation for more-detailed reading of the literature.