Stereoselective synthesis of the core structure of the protein phosphatase inhibitor dysidiolide

Stereoselective synthesis of the core structure of the protein phosphatase inhibitor dysidiolide
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DOI:
10.1016/s0040-4039(98)00702-3
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发表时间:
1998-06-04
影响因子:
1.8
通讯作者:
Waldmann, H
Waldmann, H
中科院分区:
化学4区
文献类型:
--
作者:
Brohm, D;Waldmann, H

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通过适当的二烯和α,β-不饱和醛之间的Diels-Alder反应,以高产率和高非对映异构体比率构建了蛋白磷酸酶抑制剂dysidiolide及其类似物的核心结构。 (C) 1998 Elsevier Science Ltd. 保留所有权利。
The core structure of the protein phosphatase inhibitor dysidiolide and analogs thereof were built up in high yields and with high diastereomer ratios by Diels-Alder reaction between an appropriate diene and an alpha,beta-unsaturated aldehyde. (C) 1998 Elsevier Science Ltd. All rights reserved.