AN OUTBREAK OF METAL FUME FEVER - DIAGNOSTIC USE OF URINARY COPPER AND ZINC DETERMINATIONS
AN OUTBREAK OF METAL FUME FEVER - DIAGNOSTIC USE OF URINARY COPPER AND ZINC DETERMINATIONS
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DOI：
10.1097/00043764-198312000-00011
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发表时间：
1983-01-01
影响因子：
3.2
通讯作者：
STROUBE, RB
中科院分区：
文献类型：
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作者：
ARMSTRONG, CW;MOORE, LW;STROUBE, RB
报道了在封闭、通风不良的蒸汽冷凝器中使用电割炬切割黄铜管的工人中爆发的金属烟雾热(MFF)。工人(26人)受到影响。最常见的症状是发烧(21例)、呼吸困难(23例)、寒战(21例)、头痛(21例)和恶心(19例)。工人(14人)口中有一种不寻常的甜味或金属味。8例患者临床症状仅限于喘息或罗音。在24名工人中，分别有21名和20名工人出现白细胞增多和带状细胞增多。从接触到出现症状的中位时间间隔为5小时。在冷凝器中停留1小时的3名工人中无一人患病；26名接触1小时的工人中有25人患病(P=0.001)。12名工人中有5名尿铜含量超过0.05毫克/L。这是首次报告的尿铜含量暴发。
An outbreak of metal fume fever (MFF) among workers involved in cutting brass pipes with electric cutting torches in an enclosed, poorly ventilated steam condenser was described. Workers (26) were affected. Symptoms most commonly reported were fever (21), dyspnea (23), chills (21), headache (21) and nausea (19). Workers (14) experienced the symptom of an unusual sweet or metallic taste in the mouth. Clinical signs were limited to wheezing or rales in 8 patients. Leukocytosis and an increase in band cell forms were noted in 21 and 20 of 24 workers, respectively. The median time interval between exposure and onset of symptoms was 5 h. None of 3 workers who spent < 1 h in the condenser became ill; 25 of 26 of those who spent > 1 h became ill (P = 0.001). Five of 12 workers had urine Cu levels in excess of 0.05 mg/l. This was the 1st reported outbreak of MFF for which urinary Cu levels had been measured.