STATIC AND DYNAMIC DISCHARGE PATTERNS OF BURSTING COLD FIBERS RELATED TO HYPOTHETICAL RECEPTOR MECHANISMS
STATIC AND DYNAMIC DISCHARGE PATTERNS OF BURSTING COLD FIBERS RELATED TO HYPOTHETICAL RECEPTOR MECHANISMS
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DOI：
10.1007/bf00584180
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发表时间：
1980-01-01
影响因子：
4.5
通讯作者：
HENSEL, H
中科院分区：
文献类型：
--
作者：
BRAUN, HA;BADE, H;HENSEL, H
在10 ℃至20 ℃的温度下分析猫舌神经中爆裂冷纤维的静态和动态放电模式。40.degree. C.静态爆发放电的周期仅取决于温度，而不受每次爆发的尖峰数量的影响。脉冲串内脉冲序列的终止可以通过脉冲串内间隔的持续时间来预测。不规则的脉冲模式在低静态温度下显示出单峰的间隔分布，而在高温下的不规则尖峰序列的间隔直方图有多个峰值，几乎相等的距离。对5 ° C的冷却步骤的动态响应。C分别示出了脉冲串周期的瞬时减少和每个脉冲串的尖峰数量或脉冲串持续时间的瞬时增加。脉冲群内的最大频率瞬时增加，而脉冲群内的频率衰减不断减小。在低温下，突发放电有时会被连续的高频脉冲序列中断。温度转导的模型进行了讨论的膜过程的基础上，特别是描述软体动物神经元。这些结果支持了这一假设，即爆发是由内源性振荡的受体电位触发的。假设在高温下振荡继续，但某些周期不能触发脉冲。动态冷却过程中的结果被解释为一个平坦的振荡，这是短暂的叠加由潜在的波的去极化移位。
Static and dynamic discharge patterns of bursting cold fibers in the lingual nerve of the cat were analyzed at temperatures between 10.degree.-40.degree. C. The period of the static burst discharge depends only on temperature and is not affected by the number of spikes per burst. The termination of an intraburst sequence of impulses can be predicted by the duration of the intraburst intervals. Irregular impulse patterns at low static temperatures show a unimodal interval distribution, whereas the interval histograms from irregular spike sequences at high temperatures have multiple peaks with nearly equal distances. The dynamic responses to cooling steps of 5.degree. C show a transient reduction of the burst period and a transient increase in the number of spikes per burst or the burst duration, respectively. The maximum intraburst frequencies transiently increase while the frequency decay within the burst is continuously reduced. At low temperatures, the burst discharge is sometimes interrupted by a continuous impulse sequence of high frequency. A model of temperature transduction is discussed on the basis of membrane processes which are particularly described for molluscan neurons. The results support the hypothesis that the bursts are triggered by an endogenously oscillating receptor potential. It is assumed that at high temperatures the oscillation continues but certain cycles fail to trigger impulses. The results during dynamic cooling are interpreted as a flattening of the oscillation which is transiently superposed by a depolarizing shift of the potential waves.