A prospective study of sleep duration and mortality risk in women
A prospective study of sleep duration and mortality risk in women
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DOI：
10.1093/sleep/27.3.440
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发表时间：
2004-05-01
期刊：
影响因子：
5.6
通讯作者：
Hu, FB
中科院分区：
文献类型：
--
作者：
Patel, SR;Ayas, NT;Hu, FB
研究目的：人们普遍认为，每晚8小时的睡眠对身体健康是最佳的。然而，最近的研究表明，睡眠7小时的人死亡的风险较低。为了更好地了解睡眠时间对健康的影响，我们前瞻性地研究了女性睡眠时间和死亡率之间的关系。设计：前瞻性观察研究。设置：以社区为基础。参与者：护士健康研究中的女性，她们在1986年回答了一份关于睡眠时间的邮寄问卷。干预措施：无。测量和结果：通过问卷调查、与近亲联系和国家死亡指数来确定生命状况。在这项研究的14年（1986-2000年）中，在回答初始问卷的82，969名妇女中发生了5409例死亡。报告每晚睡眠7小时的护士死亡风险最低。在调整年龄，吸烟，饮酒，运动，抑郁，打鼾，肥胖以及癌症和心血管疾病史后，睡眠少于6小时或超过7小时仍然与死亡风险增加有关。睡眠5小时或更少的相对死亡风险为1.15（95%置信区间[CI]，1.02-1.29）6小时，1.01（95% CI，0.941.08），持续7小时，1.00（对照组），持续8小时，1.12（95% CI，1.051.20），9小时或以上为1.42结论：这些结果证实了先前的研究结果，即睡眠时间为6至7小时的女性死亡风险最低。需要进一步的研究来了解睡眠时间长短对健康的影响机制。
Study Objectives: It is commonly believed that 8 hours of sleep per night is optimal for good health. However, recent studies suggest the risk of death is lower in those sleeping 7 hours. We prospectively examined the association between sleep duration and mortality in women to better understand the effect of sleep duration on health.Design: Prospective observational study.Setting: Community-based.Participants: Women in the Nurses Health Study who answered a mailed questionnaire asking about sleep duration in 1986.Interventions: None.Measurements and Results: Vital status was ascertained through questionnaires, contact with next of kin, and the National Death Index. During the 14 years of this study (1986-2000), 5409 deaths occurred in the 82,969 women who responded to the initial questionnaire. Mortality risk was lowest among nurses reporting 7 hours of sleep per night. After adjusting for age, smoking, alcohol, exercise, depression, snoring, obesity, and history of cancer and cardiovascular disease, sleeping less than 6 hours or more than 7 hours remained associated with an increased risk of death. The relative mortality risk for sleeping 5 hours or less was 1.15 (95% confidence interval [CI], 1.02-1.29) for 6 hours, 1.01 (95% CI, 0.941.08), for 7 hours, 1.00 (reference group), for 8 hours, 1.12 (95% CI, 1.051.20), and for 9 or more hours 1.42 (95% CI, 1.27-1.58).Conclusions: These results confirm previous findings that mortality risk in women is lowest among those sleeping 6 to 7 hours. Further research is needed to understand the mechanisms by which short and long sleep times can affect health.