Quantum dot (QD)-modified carbon tape electrodes for reproducible electrochemiluminescence (ECL) emission on a paper-based platform.
Quantum dot (QD)-modified carbon tape electrodes for reproducible electrochemiluminescence (ECL) emission on a paper-based platform.
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DOI：
10.1021/ac2033968
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发表时间：
2012-03
影响因子：
7.4
通讯作者：
Chuan-Guo Shi;Xia Shan;Zhong-Qin Pan;Jingjuan Xu;Chang Lu;Ning Bao;H. Gu
中科院分区：
文献类型：
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作者：
Chuan-Guo Shi;Xia Shan;Zhong-Qin Pan;Jingjuan Xu;Chang Lu;Ning Bao;H. Gu
稳定和灵敏的电致化学发光检测依赖于量子点在工作电极上的成功固定。在这里，我们报道了一种使用双面碳胶作为工作电极的新技术，以提高QD基ECL发射的稳定性和重复性。以氧化铟锡(ITO)玻璃为载体，在碳胶带上滴加干燥硫化镉量子点悬浮液，制备了硫化镉量子点修饰电极。用所制备的电极在纸基平台上进行电化学发光检测。我们用不同浓度的H(2)O(2)对我们的系统进行了测试，结果表明可以获得一致的ECL发射。我们将稳定和可重复的ECL发射归因于Cd S量子点在碳胶带上的牢固附着。根据多巴胺对以H(2)O(2)为共反应物的CdS QD体系电致发光的猝灭效应，该方法可定量测定1μM至10 mM的多巴胺浓度。我们的方法解决了基于QD的稳定ECL检测与便携式纸基分析设备的集成问题。类似的设计为低成本的电化学和ECL分析仪器提供了巨大的潜力。
Stable and sensitive electrochemiluminescence (ECL) detection relies on successful immobilization of quantum dots (QDs) on working electrodes. Herein, we report a new technique to apply double-sided carbon adhesive tape as the working electrode to improve the stability and reproducibility of QD-based ECL emission. CdS QD-modified electrodes were prepared by dropping and drying CdS QD suspension on the carbon adhesive tape supported by indium tin oxide (ITO) glass. The ECL detection was performed with the prepared electrode on a paper-based platform. We tested our system using H(2)O(2) of various concentrations and demonstrated that consistent ECL emission could be obtained. We attribute stable and reproducible ECL emission to the robust attachment of CdS QDs on the carbon adhesive tape. The proposed method could be used to quantify the concentration of dopamine from 1 μM to 10 mM based on the quenching effect of dopamine on ECL emission of CdS QD system using H(2)O(2) as the coreactant. Our approach addressed the problem in the integration of stable QD-based ECL detection with portable paper-based analytical devices. The similar design offers great potential for low-cost electrochemical and ECL analytical instruments.