Initial clinical experience with frameless stereotactic radiosurgery: Analysis of accuracy and feasibility
Initial clinical experience with frameless stereotactic radiosurgery: Analysis of accuracy and feasibility
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DOI：
10.1016/s0360-3016(01)01756-4
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发表时间：
2001-11-15
影响因子：
7
通讯作者：
Buatti, JM
中科院分区：
文献类型：
--
作者：
Ryken, TC;Meeks, SL;Buatti, JM
目的：报告一种新的图像引导无框架立体定向radiosurgery system.Methods和材料的初步临床经验：15例患者年龄从14岁到81岁不等，接受放射外科手术使用市售的无框架立体定向radiosurgery系统。病理诊断包括转移瘤（12例）、复发性原发性颅内肉瘤（1例）、复发性中枢神经系统（CNS）淋巴瘤（1例）和髓母细胞瘤伴幕上种植（1例）。根据立体定向参考阵列的图像定位和咬合板复位的可重复性评估治疗准确性。我们选择0.3分钟的向量平移误差和0.3度的旋转作为治疗前的最大容许偏差。结果：咬合板平均复位的可重复性为0.24 mm。CT定位的平均配准误差为0.5 mm，其预测等中心点处的平均误差为0.82 mm。没有患者治疗超过最大容许未对准。放射外科治疗在大约25分钟每patient.Conclusion：我们的初步临床经验，立体定向放射治疗使用红外摄像机引导系统是有前途的，证明了临床可行性和准确性相媲美的许多框架为基础的系统。(C)2001 Elsevier Science Inc.
Purpose: To report on preliminary clinical experience with a novel image-guided frameless stereotactic radiosurgery system.Methods and Materials: Fifteen patients ranging in age from 14 to 81 received radiosurgery using a commercially available frameless stereotactic radiosurgery system. Pathologic diagnoses included metastases (12), recurrent primary intracranial sarcoma (1), recurrent central nervous system (CNS) lymphoma (1), and medulloblastoma with supratentorial seeding (1). Treatment accuracy was assessed from image localization of the stereotactic reference array and reproducibility of biteplate reseating. We chose 0.3 min vector translation error and 0.3 degree rotation about each axis as the maximum tolerated misalignment before treating each are.Results: The biteplates were found on average to reseat with a reproducibility of 0.24 mm. The mean registration error From CT localization was found to be 0.5 mm, which predicts that the average error at isocenter was 0.82 mm. No patient treatment was delivered beyond the maximum tolerated misalignment. The radiosurgery treatment was delivered in approximately 25 min per patient.Conclusion: Our initial clinical experience with stereotactic radiotherapy using the infrared camera guidance system was promising, demonstrating clinical feasibility and accuracy comparable to many frame-based systems. (C) 2001 Elsevier Science Inc.