Polypropylene hollow fiber oxygenators: effect of the sorption of perfluoropolyethers.
Polypropylene hollow fiber oxygenators: effect of the sorption of perfluoropolyethers.
复制标题
聚丙烯中空纤维充氧器：全氟聚醚吸附的影响。
DOI：
10.1046/j.1525-1594.2000.06539.x
复制
发表时间：
2000
影响因子：
2.4
通讯作者：
I. Joekes
中科院分区：
文献类型：
--
作者：
F. Cassiola;P. K. Kiyohara;I. Joekes
近年来，微孔聚丙烯中空纤维的引入使血液氧合器取得了长足的进步。然而，寿命和装配问题仍未得到解决。在这项工作中，我们试图通过吸收全氟碳化合物，使纤维更疏水，从而评估氧气渗透速度。氟布林HC/25是一种全氟聚醚，以其低表面张力和对氧的高亲和力而闻名。测试了Celgard X10， X20和X30商用中空纤维。中空纤维对全氟聚醚具有较高的亲和性；肿胀明显可见。研制了一种新的氧渗透速度测量系统。吸附后氧输运速度无明显变化。用全氟聚醚浸渍的Celgard微孔中空纤维在使用2个月后没有透水现象，减少了这类纤维使用寿命中最严重的问题之一。
The introduction of microporous polypropylene hollow fibers in recent years has brought considerable advances to blood oxygenators. However, lifetime and assembly problems are still unresolved. In this work we tried to rate the oxygen permeation velocity by turning the fibers more hydrophobic through the sorption of a perfluorocarbon. Fomblin HC/25, a perfluoropolyether, is well known for its low surface tension and high affinity for oxygen. Celgard X10, X20, and X30 commercial hollow fibers were tested. The hollow fibers showed high affinity for the perfluoropolyether; swelling was clearly shown. A new system for the measurement of oxygen permeation velocity was developed. The oxygen transport velocity was not significantly changed after sorption. The Celgard microporous hollow fibers impregnated with perfluoropolyether showed no water permeation after 2 months of use, reducing one of the most serious problems in the lifetime of these types of fibers.