Trends in the management of recurrent respiratory papillomatosis in Japan
Trends in the management of recurrent respiratory papillomatosis in Japan
复制标题
日本复发性呼吸道乳头状瘤病的治疗趋势
DOI:
10.1016/j.anl.2014.10.006
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发表时间:
2015
影响因子:
1.7
通讯作者:
Yoshizaki T
中科院分区:
文献类型:
--
作者:
Murono S;Nakanishi Y;Tsuji A;Endo K;Kondo S;Wakisaka N;Yoshida H;Yoshizaki T
ObjectiveRecurrent respiratory papillomatosis (RRP) has historically been and still continues to be a difficult disease to treat. The present study aimed to characterize current practices in the treatment of RRP in Japan.MethodsA questionnaire was posted to the Department of Otolaryngology of all 80 central university hospitals in Japan.ResultsA total of 56 universities responded to the survey. Regarding the use of surgical instruments, a trend toward a preference for lasers (50 hospitals) rather than a microdebrider (16 hospitals) or cold instruments (20 hospitals) was observed. Among the 50 hospitals frequently performing laser surgery, a carbon dioxide (CO2) laser was most commonly used, followed by a potassium-titanyl-phosphate (KTP) laser. The most favored adjuvant therapy was traditional Chinese medicine. Eight of the 56 university hospitals had an experience of using cidofovir, involving a total of 28 patients.ConclusionThe present study demonstrated the current trends in the management of RRP based on a questionnaire survey in a geographical area other than the US and UK for the first time. Treatment trends were generally similar in all three areas except for the least popular use of cidofovir in Japan.