Vascular-specific growth factors and blood vessel formation
Vascular-specific growth factors and blood vessel formation
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DOI：
10.1038/35025215
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发表时间：
2000-09-14
期刊：
影响因子：
64.8
通讯作者：
Holash, J
中科院分区：
文献类型：
--
作者：
Yancopoulos, GD;Davis, S;Holash, J
最近在新发现的血管生长因子中的爆炸与用于研究血管发育的强大的新遗传方法的开发相吻合。一个新出现的规则是，所有这些因素必须完美协调地使用，以形成功能性血管。这些新发现也要求重新评估旨在调节缺血，癌症和其他病理环境中血管生长的治疗努力。
A recent explosion in newly discovered vascular growth factors has coincided with exploitation of powerful new genetic approaches for studying vascular development. An emerging rule is that all of these factors must be used in perfect harmony to form functional vessels. These new findings also demand re-evaluation of therapeutic efforts aimed at regulating blood vessel growth in ischaemia, cancer and other pathological settings.