Total synthesis of the indole alkaloid (±)- and (+)-methyl N-decarbomethoxychanofruticosinate.
Total synthesis of the indole alkaloid (±)- and (+)-methyl N-decarbomethoxychanofruticosinate.
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DOI：
10.1002/anie.201307788
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发表时间：
2013-12
影响因子：
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通讯作者：
Yi-Fei Wei;Duo Zhao;D. Ma
中科院分区：
文献类型：
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作者：
Yi-Fei Wei;Duo Zhao;D. Ma
都被关起来了：首次全合成N-decarbomethoxychanofruticosinate是通过使用Sm I2介导的分子内Reformatsky样反应来创建七元环，和分子内氧化偶联来安装笼和应变环系统。
All caged up: The first total synthesis of N-decarbomethoxychanofruticosinate is achieved by using a SmI2 -mediated intramolecular Reformatsky-like reaction to create the seven-membered ring, and an intramolecular oxidative coupling to install the caged and strained ring system.