Human auditory steady-state responses to amplitude-modulated tones: phase and latency measurements

Human auditory steady-state responses to amplitude-modulated tones: phase and latency measurements
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DOI:
10.1016/s0378-5955(99)00209-9
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发表时间:
2000-03-01
期刊:
影响因子:
2.8
通讯作者:
Picton, TW
Picton, TW
中科院分区:
医学1区
文献类型:
--
作者:
John, MS;Picton, TW

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在60 dB SPL条件下,记录了四种刺激(载波频率分别为750、1500、3000和6000 Hz)的人听稳态反应。每个载波频率由80.6、85.5、90.3或95.2 Hz的特定调制频率(f(m))调制。通过使用四种不同的记录条件,我们得到了所有排列的f(m)和f(c)的响应。将响应的相位延迟(P)展开并使用等式L = P/(360 x f(m))转换为潜伏期(L)。通过分析调制频率对响应的影响来估计在记录响应之前发生的刺激的周期数。这些计算提供了对于载波频率750、1500、3000和6000 Hz的20.7、17.7、16.1和16.1 ms的延迟。这种低载波频率和高载波频率之间约4.5 ms的潜伏期差异在许多不同的刺激操作中保持恒定:更快的调制速率(150-190 Hz),双耳而不是单耳呈现,不同的强度,单独或与其他刺激一起呈现的刺激,以及相隔0.24 Hz的调制频率。这种频率相关的延迟大于使用瞬态诱发电位测量的延迟,最有可能是因为瞬态和稳态响应如何产生以及它们的延迟如何确定的差异。(C)2000 Elsevier Science B. V.保留所有权利。
Human auditory steady-state responses were recorded to four stimuli, with carrier frequencies VE) of 750, 1500, 3000 and 6000 Hz, presented simultaneously at 60 dB SPL. Each carrier frequency was modulated by a specific modulation frequency (f(m)) of 80.6, 85.5, 90.3 or 95.2 Hz. By using four different recording conditions we obtained responses for all permutations of f(m) and f(c). The phase delays (P) of the responses were unwrapped and converted to latency (L) using the equation: L = P/(360 x f(m)). The number of cycles of the stimulus that occurred prior to the recorded response was estimated by analyzing the effect of modulation frequency on the responses. These calculations provided latencies of 20.7, 17.7, 16.1 and 16.1 ms for carrier frequencies 750, 1500, 3000 and 6000 Hz. This latency difference of about 4.5 ms between low and high carrier frequencies remained constant over many different manipulations of the stimuli: faster modulation rates (150-190 Hz), binaural rather than monaural presentation, different intensities, stimuli presented alone or in conjunction with other stimuli, and modulation frequencies that were separated by as little as 0.24 Hz. This frequency-related delay is greater than that measured using transient evoked potentials, most likely because of differences in how transient and steady-state responses are generated and how their latencies are determined. (C) 2000 Elsevier Science B.V. All rights reserved.