Long-term HIV treatment outcomes and associated factors in sub-Saharan Africa: multicountry longitudinal cohort analysis
Long-term HIV treatment outcomes and associated factors in sub-Saharan Africa: multicountry longitudinal cohort analysis
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DOI：
10.1097/qad.0000000000003270
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发表时间：
2022-08-01
期刊：
影响因子：
3.8
通讯作者：
Hamers, Raph L.
中科院分区：
文献类型：
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作者：
Inzaule, Seth C.;Kroeze, Stefanie;Hamers, Raph L.
目的：在2007年至2015年期间来自6个国家的HIV感染者的多国前瞻性队列中，我们评估了一线非核苷逆转录酶转运蛋白抗逆转录病毒治疗（ART）的长期结局，以及失访、死亡、病毒学失败和CD 4（+）T细胞恢复不完全的风险因素。研究方法：我们计算了失访、死亡、病毒学失败（VL >= 1000 cps/ml）和CD 4（+）T细胞恢复不完全（
Objective: In a multicountry prospective cohort of persons with HIV from six countries between 2007 and 2015, we evaluated long-term outcomes of first-line non-nucleoside reverse-transcriptase inhibitor-based antiretroviral therapy (ART), and risk factors for loss-to-follow-up, mortality, virological failure, and incomplete CD4(+) T-cell recovery. Methods: We calculated cumulative incidence of lost-to-follow-up, death, virological failure (VL >= 1000 cps/ml) and incomplete CD4(+) T-cell recovery (