Probiotic related Lactobacillus rhamnosus endocarditis in a patient with liver cirrhosis
Probiotic related Lactobacillus rhamnosus endocarditis in a patient with liver cirrhosis
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DOI：
10.1016/j.idcr.2018.e00439
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发表时间：
2018-01-01
期刊：
影响因子：
1.5
通讯作者：
Hofmeyr, A.
中科院分区：
文献类型：
--
作者：
Naqvi, S. S. B.;Nagendra, V.;Hofmeyr, A.
乳酸菌是胃肠道和泌尿生殖道的共生体，被认为具有低致病性。包括鼠李糖乳杆菌在内的许多物种现在都可以作为益生菌使用，近年来它们的使用得到了广泛的增加。乳酸菌有引起侵袭性感染的倾向，如菌血症和心内膜炎主要在免疫功能低下的宿主。我们报告一个致命的鼠李糖乳杆菌心内膜炎的病例，涉及一个年轻的病人，有复杂的肝硬化史和以前的艰难梭菌结肠炎；并提出了文献综述和讨论可能与全身性感染的“益生菌”配方含有乳酸菌。(C) 2018年Elsevier Ltd.出版
Lactobacilli are commensals in the gastrointestinal and genitourinary tracts and considered as having low pathogenicity. Many species including Lactobacillus rhamnosus are now available as probiotics and their use has widely increased in recent years. Lactobacilli have the propensity to cause invasive infections such as bacteraemia and endocarditis predominantly in an immunocompromised host. We report a case of fatal Lactobacillus rhamnosus endocarditis involving a young patient with a history of complicated cirrhosis and prior Clostridium difficile colitis; and present a literature review and discussion of the possible association of systemic infection with 'probiotic' formulations containing lactobacilli. (C) 2018 Published by Elsevier Ltd.