Analysis of pelvic strain in different gait configurations in a validated cohort of computed tomography based finite element models.
Analysis of pelvic strain in different gait configurations in a validated cohort of computed tomography based finite element models.
复制标题
在经过验证的基于计算机断层扫描的有限元模型队列中，分析不同步态配置下的骨盆应变。
DOI：
10.1016/j.jbiomech.2017.09.014
复制
发表时间：
2017
影响因子：
2.4
通讯作者：
C. Whyne
中科院分区：
文献类型：
--
作者：
Z. Salo;M. Beek;D. Wright;A. Maloul;C. Whyne
骨盆的功能是将上半身的负荷传递到下肢，在人体运动中至关重要。半自动、基于地标的有限元（FE）变形和映射技术消除了对分割的需求，并已证明可加速生成多个骨盆特定的骨盆FE模型，从而能够研究骨盆的力学行为。本研究的目的是产生一个实验验证队列的人类骨盆的特定的有限元模型，并使用该队列来分析骨盆在步态应变模式。使用初始分割的骨盆特定的骨盆FE模型作为源模型，使用基于地标的变形和映射技术从目标临床CT扫描生成四个以上的骨盆特定的骨盆FE模型。通过线性回归分析，将来自五种模型的FE应变与从尸体测试中获得的实验应变进行比较（R2值范围为0.70至0.93）。在五个特定的骨盆有限元模型中，观察到有限元应变分布的样本间变异性。使用经过验证的队列的特定骨盆FE模型来检查步态周期不同阶段的骨盆应变。将每个经验证的EQUEN特定FE模型重新配置为代表脚跟着地/脚跟离地和站立中期/摆动中期的步态周期阶段。在双腿站立和脚跟着地/脚跟离地模型中没有发现显著差异（p = 0.40）。在双腿站立和站立中期/摆动中期模型之间观察到一种趋势（p = 0.07），在脚跟着地/脚跟离地模型和站立中期/摆动中期模型之间发现了显著差异（p = 0.02）。在比较右侧与左侧模型时也发现了显著差异（脚跟着地/脚跟离地p = 0.14，站立中期/挥杆中期p = 0.04）。
The pelvis functions to transmit upper body loads to the lower limbs and is critical in human locomotion. Semi-automated, landmark-based finite element (FE) morphing and mapping techniques eliminate the need for segmentation and have shown to accelerate the generation of multiple specimen-specific pelvic FE models to enable the study of pelvic mechanical behaviour. The purpose of this research was to produce an experimentally validated cohort of specimen-specific FE models of the human pelvis and to use this cohort to analyze pelvic strain patterns during gait. Using an initially segmented specimen-specific pelvic FE model as a source model, four more specimen-specific pelvic FE models were generated from target clinical CT scans using landmark-based morphing and mapping techniques. FE strains from the five models were compared to the experimental strains obtained from cadaveric testing via linear regression analysis, (R2values ranging from 0.70 to 0.93). Inter-specimen variability in FE strain distributions was seen among the five specimen-specific pelvic FE models. The validated cohort of specimen-specific pelvic FE models was utilized to examine pelvic strains at different phases of the gait cycle. Each validated specimen-specific FE model was reconfigured into gait cycle phases representing heel-strike/heel-off and midstance/midswing. No significant difference was found in the double-leg stance and heel-strike/heel-off models (p = 0.40). A trend was observed between double-leg stance and midstance/midswing models (p = 0.07), and a significant difference was found between heel-strike/heel-off models and midstance/midswing models (p = 0.02). Significant differences were also found in comparing right vs. left models (heel-strike/heel-off p = 0.14, midstance/midswing p = 0.04).