Photoacoustic imaging by using a bundle of thin hollow-optical fibers

Photoacoustic imaging by using a bundle of thin hollow-optical fibers
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DOI:
10.1117/12.2209000
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发表时间:
2016-03
期刊:
--
影响因子:
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通讯作者:
A. Seki;K. Iwai;T. Katagiri;Y. Matsuura
A. Seki;K. Iwai;T. Katagiri;Y. Matsuura
中科院分区:
其他
文献类型:
--
作者:
A. Seki;K. Iwai;T. Katagiri;Y. Matsuura

文献摘要

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我们提出了一种光声成像系统,该系统由一束可弯曲的中空光纤组成,能够进行内窥镜诊断。中空纤维束包括37根纤维,内径为100μm,总直径为1.2 mm。用于光声激发的激光束在光纤束的输入端被扫描,因此在远端不需要扫描机构。此外,由于中空光纤的数值孔径很小,最终无需使用微透镜阵列即可获得高分辨率的图像。利用光纤束探头,成功地获得了鱼卵巢膜血管的光声成像,激光能量密度约为2.8mJ/cm2。
We propose a photoacoustic imaging system composed of a flexible bundle of thin hollow-optical fibers that enables endoscopic diagnosis. The hollow-fiber bundle involves 37 fibers with an inner diameter of 100 μm and the total diameter of the bundle is 1.2 mm. A laser beam for photoacoustic excitation is scanned at the input end of fiber bundle and therefore, no scanning mechanism is necessary at the distal end. In addition, owing to the small numerical aperture of hollow optical fibers, a high resolution image is obtained without using a micro-lens array at the end. By using the fiber bundle probe, photoacoustic imaging of blood vessels in the ovarian membrane of fish were successfully obtained with a laser fluence of around 2.8 mJ/cm2.