Pd-Catalyzed Dearomative Allylation of Benzyl Phosphates
Pd-Catalyzed Dearomative Allylation of Benzyl Phosphates
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DOI：
10.1021/acs.orglett.8b01807
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发表时间：
2018-07-20
期刊：
影响因子：
5.2
通讯作者：
Yamaguchi, Junichiro
中科院分区：
文献类型：
--
作者：
Komatsuda, Masaaki;Muto, Kei;Yamaguchi, Junichiro
研究了磷酸苄酯的脱芳C-C键形成。在钯/PAr 3催化剂的存在下，磷酸苄酯与硼酸烯丙酯反应以脱芳方式生成烯丙基化产物。通过Simmons-Smith环丙烷化和氧化成功地衍生化了所得的脱芳构化分子。
Dearomative C-C bond formation of benzyl phosphates has been developed. In the presence of a palladium/PAr3 catalyst, benzyl phosphates reacted with allyl borates to generate the allylated product in a dearomative fashion. The resulting dearomatized molecules were successfully derivatized by Simmons-Smith cyclopropanation and oxidation.