Antivenom: The most cost-effective treatment in the world?
Antivenom: The most cost-effective treatment in the world?
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DOI：
10.1016/j.toxicon.2010.02.012
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发表时间：
2010-06-15
期刊：
影响因子：
2.8
通讯作者：
Landon, J.
中科院分区：
文献类型：
--
作者：
Brown, N.;Landon, J.
抗蛇毒血清是唯一有效的治疗毒蛇，蝎子和其他有毒生物。不幸的是，在许多国家，这种救命药物的供应量极低，未经治疗的毒液中毒的悲惨后果给受影响的社区造成了长期的人道主义和经济负担。这种被忽视的健康危机努力与更引人注目的疾病竞争，以获得认可，研究关注和资金。改善抗蛇毒血清供应的健全战略一再失败，因为无法吸引必要的财政投资。在竞争激烈的国际卫生领域，利益相关者面临的最大挑战是证明抗蛇毒血清是一种负担得起的、具有成本效益的和值得投资的医疗资源。最近在英国的合作。非洲和南美洲的研究已经证明，将抗蛇毒血清的生产成本降低到可承受的水平是可持续的。一个简单的保健经济计算可以用来证明抗蛇毒血清在预防死亡和残疾方面的上级成本效益。这些进展可能导致抗蛇毒血清成为现代医学中最具成本效益的治疗方法之一，并为将其纳入国际卫生资助计划提供了强有力的理由。(C)2010爱思唯尔有限公司保留所有权利。
Antivenom is the only effective treatment for envenoming by snakes, scorpions and other venomous creatures. Unfortunately, supplies of this life-saving drug in many countries are critically low, and the tragic consequence of untreated envenoming exacts a chronic humanitarian and economic burden on those communities affected. This neglected health crisis struggles to compete with higher profile illnesses for recognition, research attention and funding. Sound strategies to improve the provision of antivenoms repeatedly fail because of an inability to attract the requisite financial investment. In the highly competitive international health landscape, the greatest challenge for stakeholders is to demonstrate that antivenom constitutes an affordable, cost-effective and worthwhile investment of healthcare resources. Recent collaborations in the UK. Africa and South America, have proven that lowering the production costs of antivenom to affordable levels is sustainable. A simple healthcare-economic calculation can be used to demonstrate the superior cost-effectiveness of antivenoms in preventing death and disability. These advances may lead to antivenom becoming one of the most cost-effective treatments available to modern medicine, and provides strong justification for its inclusion in international health funding initiatives. (C) 2010 Elsevier Ltd. All rights reserved.