Saliva as a diagnostic fluid
Saliva as a diagnostic fluid
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DOI：
10.1111/j.1875-595x.2007.tb00135.x
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发表时间：
2007-10-01
影响因子：
3.3
通讯作者：
Samaranayake, Lakshman
中科院分区：
文献类型：
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作者：
Samaranayake, Lakshman
唾液作为人类各种疾病的诊断液越来越受欢迎，因为它比血清有明显的优势。这些问题包括：唾液采集与静脉采集术相比具有非侵入性，即使对于有血缘关系的个体，采集也很简单，适度的培训以及对大量人群进行筛查具有成本效益的适用性。全唾液最常用于系统疾病的诊断，因为它很容易收集并含有血清成分，而腺特异性唾液可用于研究主要唾液腺的病理。广泛地说，唾液分析目前被用于诊断传染病和恶性疾病、遗传性疾病、自身免疫性疾病和内分泌疾病，以及用于评估治疗药物水平，特别是在监测药物滥用方面。这篇综述涉及唾液诊断的现状及其未来的潜力。
The use of saliva as a diagnostic fluid for various human ailments is gaining popularity as it offers distinct advantages over serum. These include the non-invasive nature of saliva collection compared with phlebotomy, simplicity of collection even for individuals with,a modest training and the cost-effective applicability for screening large populations. Whole saliva is most frequently used for diagnosis of systemic diseases since it is readily collected and contains serum constituents while gland-specific saliva is useful for investigating pathology of major salivary glands. Broadly, saliva analysis is currently used for the diagnosis of infectious and malignant diseases, hereditary disorders, autoimmune diseases, and endocrine disorders, as well as for the assessment of therapeutic drug levels, particularly in monitoring drug abuse. This review addresses the current status of salivary diagnostics and their future potential.