TESTS FOR DISTRIBUTED, NONFOCAL BRAIN ACTIVATIONS

TESTS FOR DISTRIBUTED, NONFOCAL BRAIN ACTIVATIONS
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DOI:
10.1006/nimg.1995.1024
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发表时间:
1995-09-01
期刊:
影响因子:
5.7
通讯作者:
FRISTON, KJ
FRISTON, KJ
中科院分区:
医学1区
文献类型:
--
作者:
WORSLEY, KJ;POLINE, JB;FRISTON, KJ

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大多数检测功能性大脑图像变化的方法都假设激活是集中的或非常局部的。然而,大脑对感觉运动挑战认知的反应可能是空间或解剖学上分布的。在本文中,我们考虑基于统计参数图的均方和的检验的有用性。使用模拟和真实数据评估该测试的性能,并与 gamma(2) 测试、激活区域大小的测试以及基于局部最大值强度的焦点激活测试进行比较。我们证明了均方和检验对非焦点信号更敏感,并提出它可以用来补充对焦点激活更敏感的方法。 (C) 1995 学术出版社
Most approaches to detecting changes in functional brain images assume that activations are focal or very localized. However, the brain's response to cognitive of sensorimotor challenge may be spatially or anatomically distributed. In this paper we consider the usefulness of a test based on the mean sum of squares of statistical parametric maps. The performance of this test is evaluated using simulated and real data and is compared to the gamma(2) test, a test of the size of the activated region, and a focal activation test based on the intensity of local maxima. We demonstrate that the mean sum of squares test is more sensitive to nonfocal signals and propose that it could be used to complement approaches that are more sensitive to focal activations. (C) 1995 Academic Press, Inc.