Short stature and obesity: positive association in adults but inverse association in children and adolescents
Short stature and obesity: positive association in adults but inverse association in children and adolescents
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DOI：
10.1017/s0007114508190304
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发表时间：
2009-08-14
影响因子：
3.6
通讯作者：
Mueller, Manfred J.
中科院分区：
文献类型：
--
作者：
Bosy-Westphal, Anja;Plachta-Danielzik, Sandra;Mueller, Manfred J.
身高低于平均水平的成年人患肥胖症的风险更高，也更容易患糖尿病和心血管疾病，与 BM1 无关。相比之下，身高较高的儿童肥胖的风险较高。我们假设身材矮小与不良的身体成分有关，并且身材与肥胖之间的关联因代而异。在包含 213804 名成人和 12411 名儿童和青少年的德国横断面数据库中，对身高百分位之间的超重和肥胖发生率进行了比较。在 BMI 组内分析了身高与脂肪质量百分比 (%FM)、瘦体重 BMI (LBMI；kg/m(2)) 或腰臀比（仅针对儿童）之间的关联。在成人中，BMI>30kg/m(2)的患病率随着身高百分位数的降低而逐渐增加，而在儿童和青少年中，观察到身高和体重状况之间呈正相关。身材矮小的女性和女孩的 %FM 比身材高大的受试者低 0.8-3.2%（P
Shorter than average adults are at a higher risk for obesity and are also more susceptible to diabetes and CVD, independent of BM1. In contrast, taller children have a higher risk of obesity. We hypothesised that short stature is related to adverse body composition and that the association between stature and obesity differs between generations. In a cross-sectional German database of 213804 adults and 12411 children and adolescents, the prevalence of overweight and obesity was compared between percentiles of height. The association between stature and percentage of fat mass (%FM), lean BMI (LBMI; kg/m(2)) or waist:hip ratio (in children only) was analysed within BMI groups. In adults, the prevalence of BMI >30kg/m(2) gradually increased with decreasing percentile of height whereas in children and adolescents, a positive association between height and weight status was observed. Short-stature women and girls had a 0.8-3.2% lower %FM than tall subjects (P