A One-Pot Ring-Opening/Ring-Closure Sequence for the Synthesis of Polycyclic Spirooxindoles
A One-Pot Ring-Opening/Ring-Closure Sequence for the Synthesis of Polycyclic Spirooxindoles
复制标题
用于合成多环螺吲哚的一锅法开环/闭环序列
DOI：
10.1002/chem.201900409
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Yang Hua
中科院分区：
文献类型：
--
作者：
Ren Ji-Wei;Zhao Qing-Lan;Xiao Jun-An;Xia Peng-Ju;Xiang Hao-Yue;Chen Xiao-Qing;Yang Hua
One‐pot ring‐opening/ring‐closure process of combining methyleneindolinone with 3‐aminooxindole has been developed in this work. Novel polycyclic spirooxindoles were efficiently assembled under mild conditions in high yields (up to 95 %) with moderate to good diastereoselectivities (up to >95:5 d.r.) through simple filtration.
