PRELIMINARY CRITERIA FOR THE CLASSIFICATION OF SYSTEMIC-SCLEROSIS (SCLERODERMA)
PRELIMINARY CRITERIA FOR THE CLASSIFICATION OF SYSTEMIC-SCLEROSIS (SCLERODERMA)
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DOI：
10.1002/art.1780230510
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发表时间：
1980-01-01
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对系统性硬化症的早期诊断病例和系统性红斑狼疮、多发性肌炎/皮肌炎和雷诺现象的比较患者进行了一项多中心、正在进行的研究，以制定系统性硬化症的分类标准。提出了初步标准，即发现唯一的主要标准（近端硬皮病）或2个或多个次要标准：指端硬皮病;指端凹陷性瘢痕或远端指垫物质丢失;双侧基底肺纤维化。当应用于病例和对照患者时，这些建议的标准对明确的系统性硬化症的敏感性为97%，特异性为98%。
A multicenter, ongoing study of early-diagnosed cases of systemic sclerosis and comparison patients with systemic lupus erythematosus, polymyositis/dermatomyositis and Raynaud''s phenomenon was conducted in order to develop classification criteria for systemic sclerosis. Preliminary criteria are proposed, namely, the finding of the sole major criterion, (proximal scleroderma) or 2 or more of the minor criteria: sclerodactyly; digital pitting fingertip scars or loss of substance of the distal finger pad; and bilateral basilar pulmonary fibrosis. When applied to the case and comparison patients, these proposed criteria had a 97% sensitivity for definite systemic sclerosis and 98% specificity.