One-pot quinazolin-4-ylidenethiourea synthesis via N-(2-cyanophenyl)benzimidoyl isothiocyanate
One-pot quinazolin-4-ylidenethiourea synthesis via N-(2-cyanophenyl)benzimidoyl isothiocyanate
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DOI：
10.3390/60700574
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发表时间：
2001-07-01
期刊：
影响因子：
4.6
通讯作者：
Pazdera, P
中科院分区：
文献类型：
--
作者：
Fathalla, WM;Cajan, M;Pazdera, P
N-(2-氰基苯基)苯并亚胺基异硫氰酸酯(3)与仲胺一锅法合成了1，1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas(8)。产物经氨基转移反应。化合物8a-8g经FTIR、H-1-核磁共振、C-13-核磁共振、质谱学和X-射线结晶学确证。
1,1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas (8) were synthesized in a one pot reaction of N-(2-cyanophenyl)benzimidoyl isothicyanate (3) with secondary amines. The products underwent transamination reactions. Compounds 8a-8g were identified by FTIR, H-1-NMR, C-13-NMR, mass spectroscopy and X-ray crystallography.