Cardiac receptors in the dog, with particular reference to two types of afferent ending in the ventricular wall
Cardiac receptors in the dog, with particular reference to two types of afferent ending in the ventricular wall
复制标题
狗的心脏受体，特别是心室壁中的两种类型的传入末梢
DOI：
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发表时间：
1964
期刊：
影响因子：
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通讯作者：
C. Kidd
中科院分区：
文献类型：
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作者：
H. Coleridge;J. Coleridge;C. Kidd
关于心脏心房壁的传入末梢，人们已经了解很多。组织学研究已经对其外观和分布进行了描述，而电生理学研究使它们的冲动活动得到了广泛的描述（Paintal 评论，1963）。关于心室中的受体知之甚少。组织学上已在心室壁中证实了多种传入末梢（参见讨论），但没有任何明确定义的分布模式，例如在心房中发现的 Nonidez (1937)。心室纤维的冲动活动已在猫（Paintal，1955）和青蛙（Kolatat，Kramer & Miihl，1957）中进行了详细描述，但迄今为止还没有对狗中这些纤维的详细描述。鉴于在这种动物中进行了许多通过扩张心室来引起反射效应的尝试（例如 Salisbury、Cross 和 Rieben，1960），这是令人惊讶的。本文描述了在狗身上记录放电心室纤维脉冲的实验，类似于 Paintal (1955) 在猫身上描述的那些。此外，其他纤维也遇到不规则类型的放电，其传入端靠近心室的心外膜表面。对心房受体的分布和神经连接也进行了一些进一步的观察。
A great deal is known about afferent endings in the atrial walls of the heart. Histological studies have yielded descriptions of their appearance and distribution, and electrophysiological investigations have enabled their impulse activity to be extensively described (reviewed by Paintal, 1963). Less is known about receptors in the ventricles. A variety of afferent endings have been demonstrated histologically in the ventricular wall (see Discussion) but without any clearly defined pattern of distribution such as Nonidez (1937) found in the atrium. The impulse activity of ventricular fibres has been described in detail in cats (Paintal, 1955) and in frogs (Kolatat, Kramer & Miihl, 1957) but there has so far been no detailed account of these fibres in the dog. This is surprising in view of the many attempts made in this animal to evoke reflex effects by distending the ventricle (e.g. Salisbury, Cross & Rieben, 1960). The present paper describes experiments in which impulses were recorded in dogs from ventricular fibres with a cardiac rhythm of discharge, similar to those described by Paintal (1955) in the cat. In addition, other fibres were encountered with an irregular type of discharge and whose afferent endings were near the epicardial surface of the ventricles. Some further observations were also made on the distribution and nerve connexions of receptors in the atria.