Trichomoniasis and other sexually transmitted infections: results from the 2001-2004 National Health and Nutrition Examination Surveys.
Trichomoniasis and other sexually transmitted infections: results from the 2001-2004 National Health and Nutrition Examination Surveys.
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DOI：
10.1097/olq.0b013e3181b38a4b
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发表时间：
2009-12
影响因子：
3.1
通讯作者：
Peipert JF
中科院分区：
文献类型：
--
作者：
Allsworth JE;Ratner JA;Peipert JF
为了在全国代表性样本中估计阴道毛滴虫感染 (TV) 与六种性传播感染之间的关联：衣原体、淋病、单纯疱疹病毒（1 型和 2 型）、梅毒和艾滋病毒。我们使用国家健康和营养检查调查 (NHANES) 的数据，结合 2001-2002 年和 2003-2004 年的数据来估计美国平民、非机构化人口中的女性电视与性传播感染之间的关联。最终样本包括来自 3,648 名女性的数据，这些数据经过加权后代表了 65,563,298 名年龄在 14 岁至 49 岁之间的美国女性的经历。使用罕见性传播感染（< 10%；衣原体、梅毒和人类免疫缺陷病毒 (HIV)）的逻辑回归和常见性传播感染（单纯疱疹病毒 (HSV) 1 型和 1 型）的泊松回归估计粗略和调整后的相对风险。 2）。使用Stata（版本9.2）进行统计分析。滴虫病患病率为3.2%，过去一个月有超过80%的病例无症状。所有检查的性传播感染（衣原体、淋病、HSV-1、HSV-2、梅毒和艾滋病毒）在滴虫检测呈阳性的女性中更为常见。在调整种族/民族、年龄和最近的性伴侣后，HSV-1（RR = 1.20，95% CI 1.09，1.34）和HSV-2（RR = 1.51，95% CI 2.32，3.23）与滴虫病显着相关。在粗略分析中，滴虫病女性中，梅毒螺旋体检测呈阳性的几率要高出 6 倍（95% CI 2.07, 18.8），HIV 检测的几率要高出 13 倍（95% 2.88, 59.1），但在调整潜在的混杂因素后，这些估计值大大减弱。滴虫病与并发性传播感染显着相关。
To estimate the association between Trichomonas vaginalis infection (TV) and six sexually transmitted infections: chlamydia, gonorrhea, herpes simplex virus (Types 1 and 2), syphilis and HIV in a nationally representative sample. We used data from the National Health and Nutrition Examination Survey (NHANES) combining the 2001–2002 and 2003–2004 waves to estimate the association between TV and STIs among women in the civilian, non-institutionalized US population. The final sample included data from 3,648 women, which when weighted, represents the experience of 65,563,298 US women between the ages of 14 and 49. Crude and adjusted relative risks were estimated using logistic regression for rare STIs (< 10%; chlamydia, syphilis and human immunodeficiency virus (HIV)) and Poisson regression for common STIs (herpes simplex virus (HSV) types 1 and 2). Statistical analyses were conducted using Stata (version 9.2). The prevalence of trichomoniasis was 3.2% with over 80% of cases asymptomatic in the past month. All STIs examined (chlamydia, gonorrhea, HSV-1, HSV-2, syphilis and HIV) were more common among women with a positive test for trichomoniasis. HSV-1 (RR = 1.20, 95% CI 1.09, 1.34) and HSV-2 (RR= 1.51, 95% CI 2.32, 3.23) were significantly associated with trichomoniasis after adjusting for race/ethnicity, age and recent sexual partners. In crude analyses, a positive treponemal test was 6 times (95% CI 2.07, 18.8) more common and HIV was 13 times (95% 2.88, 59.1) more common among women with trichomoniasis, but these estimates were greatly attenuated after adjustment for potential confounders. Trichomoniasis is significantly associated with concurrent STI.