THE EFFECT OF MALE HORMONE ON AGGRESSIVE BEHAVIOR IN MICE
THE EFFECT OF MALE HORMONE ON AGGRESSIVE BEHAVIOR IN MICE
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DOI：
10.1086/physzool.20.4.30151969
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发表时间：
1947-01-01
期刊：
影响因子：
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通讯作者：
BEEMAN, EA
中科院分区：
文献类型：
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作者：
BEEMAN, EA
正常[雄性]C57黑鼠的攻击行为模式与正常[雄性]Bagg白化小鼠的攻击行为模式在性质上相似。正常的C57黑鼠表现出更强的攻击性，并表现出比白化小鼠更频繁的战斗趋势。在每一轮测试中，白化老鼠摇尾巴的次数比黑老鼠多。比较两菌株的攻击次数/（尾摇+攻击次数）的比值，两菌株之间的差异非常显著；P < 0.0001 （t = 11 +）。两种品系的正常小鼠所表现出的攻击性行为模式的组成部分的频率会发生波动。这种变化可能是由于一开始整个群体的攻击性，使老鼠表现出较少的攻击性，而随后与不具攻击性的老鼠相遇，使老鼠恢复了表现出攻击性行为的能力。在雄激素植入的去势体中也出现了类似的攻击性变化。随着总体攻击性的增强，梳理毛发的次数会减少，反之亦然。在C57黑白化和Bagg白化[雄性]小鼠未成熟或成年时进行阉割，结果导致这些小鼠无法表现出攻击行为，无论在隔离时年龄大小，在阉割和初次接触之间间隔25天或更长时间。丙酸睾酮颗粒亚切。植入将诱导两种阉割小鼠在质量和数量上表现出与同类正常[雄性]小鼠相同的攻击行为特征。从阉割体中去除雄激素颗粒，大多数小鼠的攻击性几乎立即停止。在雄激素治疗开始后，额外的接触可能会刺激阉割的老鼠在一次接触中表现出更强的攻击性，因为任何2只老鼠在4只老鼠的一组中比3只老鼠在一次特定的接触中表现出更多的摇尾，攻击和战斗。该税。表现出的攻击性行为与精囊和前列腺的大小正相关，因为两者都受到amt的影响。雄激素的存在。
The aggressive behavior pattern of normal [male] C57 black mice is qualitatively similar to that of normal [male] Bagg albino mice. Normal C57 black mice display more attacking and exhibit a general trend to fight more frequently than do the albino mice. The albino mice rattle their tails a greater number of times in each round than do the black mice. When the ratio, attacks/(tail rattles + attacks) in both strains is compared, the difference between the 2 strains is highly significant; P < 0.0001 (t = 11 +). Fluctuations occur in the frequency with which the components of the aggressive behavior pattern are displayed by normal mice of both strains. Such changes may result from the initial aggressiveness of the group as a whole, conditioning the mice to show less aggression, and subsequent encounters with nonaggressive mice restoring the ability of mice to display aggressive behavior. Similar variations in aggressiveness occur in androgen-implanted castrates. As general aggressiveness increases, there is a decrease in grooming and vice versa. Castration of C57 black and Bagg albino [male] mice as immature animals or as adults results in the failure of these mice to display aggressive behavior, regardless of age at isolation when a period of 25 or more days elapses between castration and initial encounters. Testosterone propionate pellets subcut. implanted will induce castrate mice of both strains to display aggressive behavior characteristic in quality and quantity of normal [male] mice of comparable strain. Removal of androgen pellets from castrates results in an almost immediate cessation of aggressiveness in the majority of mice. After androgen therapy has begun, additional encounters may stimulate castrate mice to exhibit more aggressiveness within a single encounter, since any 2 mice which were members of sets of 4 mice displayed more tail-rattling, attacking and fighting in a given encounter than did mice which were members of sets of 3. The amt. of aggressive behavior displayed is positively correlated with the size of the seminal vesicles and prostate glands, since both are affected by amt. of androgen present.