HISTIOCYTOID HEMANGIOMA OF THE HEART WITH PERIPHERAL EOSINOPHILIA
HISTIOCYTOID HEMANGIOMA OF THE HEART WITH PERIPHERAL EOSINOPHILIA
复制标题
DOI：
10.1002/1097-0142(19850615)55:12
复制
发表时间：
1985-01-01
期刊：
影响因子：
6.2
通讯作者：
CHEN, JS
中科院分区：
文献类型：
--
作者：
KUO, TT;HSUEH, S;CHEN, JS
心脏组织细胞样血管瘤的报告，这是偶然发现的一名男子异常高嗜酸性粒细胞。肿瘤切除后嗜酸性粒细胞显著减少。肿瘤细胞的“组织细胞样”或“上皮样”外观和空泡细胞的存在是特征性的显微镜特征。该肿瘤的内皮起源通过因子VIII相关抗原的阳性免疫染色和胞浆内管腔形成、丰富的胞浆细丝、胞饮小泡和突出的基底层的超微结构证实。有丝分裂活性、细胞多形性和肿瘤坏死的存在提高了其恶性潜能的可能性。发生在心脏的肿瘤，临床上可能被误认为粘液瘤，病理上可能被误认为转移癌。
A histiocytoid hemangioma of the heart is reported, which was found incidentally in a man with unusually high eosinophilia. The eosinophilia subsided dramatically following removal of the tumor. The "histiocytoid" or the "epithelioid" appearance of the tumor cells and the presence of vacuolated cells were the characteristic microscopic features. The endothelial origin of this tumor was verified by positive immunostaining for factor VIII-related antigen and ultrastructural demonstration of intracytoplasmic lumen formation, abundant cytoplasmic filaments, pinocytotic vesicles and prominent basal lamina. The presence of mitotic activity, cellular plemorphism and tumor necrosis raised the possibility of its malignant potential. The occurence of this tumor in the heart may be mistaken for a myxoma clinically and a metastatic carcinoma pathologically.