Understanding suboptimal human papillomavirus vaccine uptake among ethnic minority girls.
Understanding suboptimal human papillomavirus vaccine uptake among ethnic minority girls.
复制标题
了解少数民族女孩中次优的人乳头瘤病毒疫苗的摄取。
DOI：
10.1158/1055-9965.epi-11-0267
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发表时间：
2011-07
期刊：
影响因子：
--
通讯作者：
Singhal R
中科院分区：
文献类型：
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作者：
Bastani R;Glenn BA;Tsui J;Chang LC;Marchand EJ;Taylor VM;Singhal R
HPV疫苗的推出代表了宫颈癌一级预防的突破。然而，人们对可能从疫苗中受益最多的美国低收入人群、少数族裔和移民人群的疫苗接种情况及其相关性知之甚少。 2009 年 1 月至 11 月期间，通过洛杉矶县公共卫生部妇女健康办公室服务转介热线，以六种语言对符合疫苗接种资格的女孩（9 至 18 岁）的母亲进行了电话访谈（N=490）。对 HPV 和疫苗的认识、知识、信念、障碍以及女儿的疫苗接种情况进行了评估。样本由低收入、无保险、少数民族和移民妇女组成。只有 29% 的女儿开始接种疫苗，11% 的女儿接种了全部三剂疫苗。未观察到启动率或完成率存在种族差异。在 HPV 认知、感知风险和其他免疫相关信念方面观察到种族差异。启动的最强预测因素是疫苗意识（OR=12.00）。女儿的年龄和报告可接受的疫苗接种年龄较小与开始接种呈正相关。未接种疫苗的女孩的母亲表示，缺乏有关疫苗的信息以做出决定（66%），也不知道在哪里可以获得疫苗（74%）。该样本中的疫苗接种率低于州和国家的估计值，并且与疫苗意识水平较低有关。干预措施，包括针对文化的信息传递，可能有助于增强 HPV 疫苗知识、改变与疫苗相关的信念并提高接种率。我们的研究结果为制定干预措施以解决高危人群 HPV 疫苗接种效果不佳的问题提供了宝贵的指导。
The introduction of HPV vaccines represents a breakthrough in the primary prevention of cervical cancer. However, little is known about vaccination uptake and correlates among U.S. low-income, ethnic minority and immigrant populations who may benefit most from the vaccine. Telephone interviews (N=490) were conducted in six languages between January and November 2009 among mothers of vaccine-eligible girls (ages 9–18) using the Los Angeles County Department of Public Health, Office of Women’s Health service referral hotline. HPV and vaccine awareness, knowledge, beliefs, barriers, and daughter’s vaccine receipt were assessed. The sample consisted of low-income, uninsured, ethnic minority and immigrant women. Only 29% of daughters initiated the vaccine and 11% received all three doses. No ethnic differences were observed in initiation or completion rates. Ethnic differences were observed in HPV awareness, perceived risk, and other immunization related beliefs. The strongest predictor of initiation was vaccine awareness (OR=12.00). Daughter’s age and reporting a younger acceptable age for vaccination were positively associated with initiation. Mothers of unvaccinated girls reported lacking information about the vaccine to make a decision (66%) and not knowing where they could obtain the vaccine (74%). Vaccination rates in this sample were lower than state and national estimates, and were associated with low levels of vaccine awareness. Interventions, including culturally targeted messaging, may be helpful for enhancing HPV vaccine knowledge, modifying vaccine-related beliefs and increasing uptake. Our findings provide valuable guidance for developing interventions to address sub-optimal HPV vaccination in high risk groups.