Membrane fusion through point defects in bilayers.
Membrane fusion through point defects in bilayers.
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通过双层中的点缺陷实现膜融合。
DOI：
10.1126/science.7233185
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Yeagle,PL
中科院分区：
文献类型：
--
作者：
Hui,SW;Stewart,TP;Boni,LT;Yeagle,PL
冻融可诱导卵磷脂和大豆磷脂酰乙醇胺混合物双层膜的融合。通过冷冻断裂电子显微镜观察双层膜之间的接触点，并在熔融条件下通过磷-31核磁共振检测各向同性分子运动平均。点缺陷结构的分子模型提出了作为一个中间阶段的融合。
Fusion between bilayers of mixed egg phosphatidylcholine and soybean phosphatidylethanolamine was induced by freezing and thawing. Contact points between bilayers were observed by freeze fracture electron microscopy, and isotropic molecular motional averaging was detected by phosphorus-31 nuclear magnetic resonance under fusion conditions. A molecular model of point defect structure is proposed as an intermediate stage of fusion.