An epidemiologic study of MRI and low back pain in 13-year-old children
An epidemiologic study of MRI and low back pain in 13-year-old children
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DOI：
10.1097/01.brs.0000157424.72598.ec
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发表时间：
2005-04-01
期刊：
影响因子：
3
通讯作者：
Bendix, T
中科院分区：
文献类型：
--
作者：
Kjaer, P;Leboeuf-Yde, C;Bendix, T
研究设计。普通人群的横断面队列研究。目的。描述13岁儿童“异常”腰椎磁共振成像（MRI）结果与腰痛（LBP）之间的关系。摘要和背景资料。我们对腰椎MRI的分布以及它们与青少年腰痛的关系知之甚少。从439例儿童的MRI研究中发现椎间盘异常、神经根受损、终板改变和前滑脱。LBP是通过结构化访谈确定的。关联以比值比（OR）表示。大约1/3的受试者有椎间盘退变的迹象。上3个腰椎间盘的信号强度降低和不规则核形状与上个月的腰痛显著相关（OR, 2.5 - 3.6），而信号强度降低和腰5 - S1椎间盘突出与求医有关（OR分别为2.8和7.7）。终板与L3椎间盘相关的变化与腰痛月份和求医有关（OR，在9.7和22.2之间）。L5期前滑脱与就医相关（OR, 4.3）。性别间存在明显差异：男孩上腰椎退变性椎间盘改变与腰痛的相关性更强，而女孩下腰椎椎间盘异常与求医的相关性更强。在儿童中，椎间盘退行性表现相对常见，有些与腰痛有关。这似乎存在性别差异。腰椎间盘突出、终板改变和腰椎前滑脱与寻求腰痛治疗密切相关。
Study Design. Cross-sectional cohort study of a general population.Objective. To describe associations between "abnormal" lumbar magnetic resonance imaging (MRI) findings and low back pain (LBP) in 13-year old children.Summary and Background Data. Very little is known about the distribution of lumbar MRI findings and how they are associated with LBP in youngsters.Methods. Disc abnormalities, as well as nerve root compromise, endplate changes, and anterolisthesis were identified from MRI studies of 439 children. LBP was identified from structured interviews. Associations are presented as odds ratios ( OR).Results. Signs of disc degeneration were noted in approximately 1/3 of the subjects. Reduced signal intensity and irregular nucleus shape in the upper 3 lumbar discs were significantly associated with LBP within the last month ( OR, 2.5 - 3.6), whereas reduced signal intensity and disc protrusion at L5 - S1 were associated with seeking care ( OR, 2.8 and 7.7, respectively). Endplate changes in relation to the L3 discs were associated with LBP month and seeking care ( OR, between 9.7 and 22.2). Anterolisthesis at L5 was associated with seeking care ( OR, 4.3). There were obvious differences between genders: degenerative disc changes in the upper lumbar spine were more strongly associated with LBP in boys, while disc abnormalities in the lower lumbar spine were more strongly associated with seeking care in girls.Conclusions. In children, degenerative disc findings are relatively common, and some are associated with LBP. There appears to be a gender difference. Disc protrusions, endplate changes, and anterolisthesis in the lumbar spine were strongly associated with seeking care for LBP.