METASTATIC LESIONS OF THE BRAIN - IMAGING WITH MAGNETIZATION-TRANSFER
METASTATIC LESIONS OF THE BRAIN - IMAGING WITH MAGNETIZATION-TRANSFER
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DOI：
10.1148/radiology.191.3.8184068
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发表时间：
1994-06-01
期刊：
影响因子：
19.7
通讯作者：
MCGOWAN, JC
中科院分区：
文献类型：
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作者：
BOORSTEIN, JM;WONG, KT;MCGOWAN, JC
目的：应用常规自旋回波（SE）和磁化转移（MT）磁共振（MR）成像研究脑孤立性转移性病变。材料与方法：在15例患者中，计算转移灶中心和周围的MT比率（MTR），以及远端邻近白质，从病变周围放射状地到最远处的皮层。为了提供控制值，还计算了相对半球的镜像位置。结果：转移灶内及周围的MTRs均降低。转移灶远端MTRs也低于控制值，即使在给予加多戊二胺之前和之后获得的SE MR图像上没有发现异常。结论：MT能够在SE - MR图像上未见的转移性病变患者中显示白质异常。这些变化可以在远远的远端病变和水肿周围的白质中发现。
PURPOSE: To study solitary metastatic lesions of the brain with routine spin-echo (SE) and magnetization transfer (MT) magnetic resonance (MR) imaging.MATERIALS AND METHODS: In 15 patients with such lesions, the MT ratio (MTR) was calculated in the center and at the periphery of the metastatic lesion, and distally in adjacent white matter, from the periphery of the lesion radially to the most distant cortex. It also was calculated for mirror-image locations in the opposite hemisphere to provide control values.RESULTS: MTRs were decreased in and immediately around the site of the metastatic focus. MTRs also were lower than control values far distal to the metastatic focus, even when no abnormality was seen on SE MR images obtained before and those obtained after administration of gadopentetate dimeglumine.CONCLUSION: MT enables demonstration of white matter abnormalities in patients with metastatic lesions not seen on SE MR images. These changes can be found in white matter far distal to the lesion and surrounding areas of edema.