Classification of vocal tremor using updated consensus-based tremor classification criteria.

Classification of vocal tremor using updated consensus-based tremor classification criteria.
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DOI:
10.1002/lio2.544
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发表时间:
2021-04
影响因子:
1.9
通讯作者:
Barkmeier-Kraemer JM
Barkmeier-Kraemer JM
中科院分区:
医学3区
文献类型:
--
作者:
Torrecillas V;Dwenger K;Barkmeier-Kraemer JM

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本研究使用国际帕金森和运动障碍学会(IPMDS)发布的震颤分类标准,包括美国耳鼻咽喉头颈外科学会(AAO‐HNS)的喉部特征,对声带震颤(VT)患者的临床表型进行了表征。从2017年至2019年的参与者病历中提取VT表型描述符。临床表型描述符包括:(a)首次就诊的主诉和学科,(B)人口统计学,(c)震颤体分布、状况、频率和进展,(d)加重/缓解因素,(e)治疗方法和(g)神经系统合并症。进行了描述性统计。在179例符合入选标准的患者中,2/3例为女性;震颤发作影响嗓音(43%)或肢体(32%),2/3例记录震颤持续时间为3年或更长。原发性室性心动过速患者首先就诊于耳鼻喉科或言语语言病理学(59%),而原发性肢体/头部震颤患者首先就诊于神经病学(36%)。记录通常忽略震颤临床特征,例如(a)观察到的震颤状况(64%),(B)喉部特征(64%)和(c)震颤频率(92%)。因此,VT分类基于49%患者的合并症(即原发性震颤(48%)、肌张力障碍(72%)和帕金森病(100%)),32%的患者没有足够的文件进行分类。大多数VT患者无法根据记录的临床特征进行分类,这突出表明需要对影响语言结构的震颤进行一致的多学科评估。震颤的主要部位决定了第一个观察到的学科。最常见的VT分类包括特发性震颤(47%)、肌张力障碍(28%)、帕金森综合征(7%)和孤立性VT(19%)。4.本研究使用国际帕金森和运动障碍学会(IPMDS)发布的震颤分类标准,包括美国耳鼻咽喉头颈外科学会(AAO‐HNS)的喉部特征,对声带震颤(VT)个体临床表型的电子病历文件进行了表征。大多数室性心动过速患者无法分类,这突出表明需要对影响言语结构的震颤进行一致的多学科评估和记录。在105名能够分类的患者中,47%被归类为特发性震颤,28%被归类为肌张力障碍,19%被归类为孤立性室性心动过速,7%被归类为帕金森氏症;除原发性震颤组(47%)外,所有患者中2/3为女性,孤立性声带震颤的发病较晚与其他组(53 - 58岁)相比,原发性VT组(67岁)首先就诊于耳鼻咽喉/语言病理学(59%),而原发性肢体震颤组首先就诊于神经学(36%)。
This study characterized the clinical phenotypes of individuals with vocal tremor (VT) using tremor classification criteria published by the International Parkinson and Movement Disorder Society (IPMDS) including laryngeal features from the American Academy of Otolaryngology—Head and Neck Surgery (AAO‐HNS). VT phenotypic descriptors were extracted from participant medical records from 2017 to 2019. Clinical phenotype descriptors included the: (a) chief complaint and discipline for the first appointment, (b) demographics, (c) tremor body distribution, condition, frequency, and progression, (d) exacerbating/alleviating factors, (e) treatment approaches, and (g) neurologic comorbidities. Descriptive statistics were conducted. Of 179 meeting inclusion criteria, 2/3 were female; tremor onset affected voice (43%) or extremity (32%) and 2/3 were documented with tremor duration of 3 years or more. Those with primary VT first saw otolaryngology or speech language pathology (59%), whereas those with primary extremity/head tremor first saw neurology (36%). Documentation commonly omitted tremor clinical features such as (a) observed conditions of tremor (64%), (b) laryngeal features (64%), and (c) tremor frequency (92%). Thus, VT classification was based on comorbidity in 49% of patients (ie, essential tremor (48%), dystonia (72%), and Parkinson's disease (100%)) and 32% had inadequate documentation to classify. The majority of individuals with VT were unable to be classified based on documented clinical features highlighting the need for consistent multidisciplinary assessment of tremor affecting speech structures. The primary site of tremor determined the first discipline seen. Most commonly classified VT categories included essential tremor (47%), dystonia (28%), Parkinsonism (7%), and isolated VT (19%). 4. This study characterized electronic medical record documentation of clinical phenotypes of individuals with vocal tremor (VT) using tremor classification criteria published by the International Parkinson and Movement Disorder Society (IPMDS) including laryngeal features from the American Academy of Otolaryngology – Head and Neck Surgery (AAO‐HNS). The majority of individuals with VT were unable to be classified, highlighting the need for consistent multi‐disciplinary assessment and documentation of tremor affecting speech structures. Of 105 individuals able to be classified, 47% were classified as essential tremor, 28% as dystonia, 19% as isolated VT and 7% as Parkinsonism; 2/3 were female for all but the essential tremor group (47%), isolated vocal tremor had later onset of tremor (67 years) compared to other groups (53‐58 years), and those with primary VT first saw otolaryngology/speech‐language pathology (59%) whereas those with primary extremity tremor first saw neurology (36%).
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