Ovarian yolk sac tumor with epithelial tumor component in a postmenopausal woman - case report and literature review.

Ovarian yolk sac tumor with epithelial tumor component in a postmenopausal woman - case report and literature review.
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绝经后妇女卵巢卵黄囊肿瘤伴上皮肿瘤成分——病例报告和文献综述。

DOI:
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发表时间:
2020
影响因子:
1.4
通讯作者:
S. Jang
S. Jang
中科院分区:
医学4区
文献类型:
--
作者:
H. Ahn;M. Oh;Hyundeuk Cho;Ji;H. Lee;S. Jeon;S. Jang

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卵巢卵黄囊肿瘤是一种常见的生殖细胞肿瘤,好发于年轻女性。卵黄囊瘤在老年妇女中并不常见,且大多数合并其他上皮性肿瘤成分,包括卵巢样癌或浆液性癌。在这里,我们报告了一个非常罕见的情况下,卵黄囊肿瘤与粘液性肿瘤和大细胞神经内分泌癌成分的绝经后妇女,这是第三个卵黄囊肿瘤的情况下,神经内分泌肿瘤元素的老年妇女。一位82岁女性因腹胀来我院就诊。腹部计算机断层扫描(CT)显示一个实性和囊性肿块,最大直径约9.0 cm。全子宫切除术,双侧输卵管卵巢切除术和腹膜转移病灶切除活检。组织学评价显示恶性卵巢肿瘤由多种肿瘤成分组成,包括卵黄囊肿瘤、多灶性粘液性癌区的粘液性肿瘤和大细胞神经内分泌癌。手术后,患者拒绝进一步治疗,9个月后盆腔腹膜和左锁骨上淋巴结复发。
Ovarian yolk sac tumors are common germ cell tumors usually arising in young women. Yolk sac tumors in elderly women are infrequently encountered and most of them are combined with other epithelial tumor components including endometrioid carcinoma or serous carcinoma. Here, we report an extremely rare case of a yolk sac tumor with mucinous tumor and large cell neuroendocrine carcinoma components in a postmenopausal woman, which is the third yolk sac tumor case with a neuroendocrine tumor element in an elderly woman. An 82-year-old female visited our hospital due to abdominal distention. Abdominal computed tomography (CT) demonstrated a solid and cystic mass, measuring about 9.0 cm in the largest diameter. A total hysterectomy with bilateral salpingo-oophorectomy and excisional biopsy of the peritoneal metastatic lesions was performed. Histologic evaluation revealed a malignant ovarian tumor composed of a variety of tumor components, including a yolk sac tumor, a mucinous tumor with multifocal mucinous carcinomatous areas, and a large-cell neuroendocrine carcinoma. After surgery, the patient refused further treatment and the disease recurred in the pelvic peritoneum and a left supraclavicular lymph node nine months later.
DOI: --
发表时间: 2020
期刊:
影响因子: --
作者:
大谷知之;宮川知保;木村雅友;長廻錬;佐藤隆夫;松村謙臣;伊藤彰彦
通讯作者: 伊藤彰彦