An enzymatic route to 5-deoxy-5-[18F]fluoro-D-ribose, a [18F]-fluorinated sugar for PET imaging
An enzymatic route to 5-deoxy-5-[18F]fluoro-D-ribose, a [18F]-fluorinated sugar for PET imaging
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DOI：
10.1039/b919364b
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发表时间：
2010-01-01
影响因子：
4.9
通讯作者：
O'Hagan, David
中科院分区：
文献类型：
--
作者：
Onega, Mayca;Domarkas, Juozas;O'Hagan, David
描述了一种涉及氟化酶的有效的两步一锅生物转化用于合成5-脱氧-5 [F-18]氟核糖，5-脱氧-5 [F-18]氟核糖是一种适用于正电子发射断层扫描（PET）应用的新型[F-18]氟化糖。
An efficient two-step, one-pot, biotransformation involving the fluorinase enzyme is described for the synthesis of 5-deoxy-5[F-18]fluororibose, a novel [F-18]-fluorinated sugar suitable for positron emission tomography (PET) applications.