Developmental studies of thalamocortical and commissural connections in the rat somatic sensory cortex
Developmental studies of thalamocortical and commissural connections in the rat somatic sensory cortex
复制标题
大鼠躯体感觉皮层丘脑皮质和连合连接的发育研究
DOI：
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发表时间：
1978
期刊：
影响因子：
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通讯作者：
E. Jones
中科院分区：
文献类型：
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作者：
S. Wise;E. Jones
用放射自显影、轴突变性和辣根过氧化物酶纤维示踪法研究了大鼠丘脑皮质向躯体感觉皮质的投射的组织、发育和潜在可塑性。在成年动物中，丘脑皮质终末主要集中在第I层和第IV层以及第VI层的上部。在第IV层和第VI层终止的纤维来自与终止于第I层的纤维不同的区域。250-450μm宽的纤维和终末仅分布在SI皮质中含有致密的IV层颗粒细胞聚集的部分，而不分布到中间的、较少颗粒性的和连合连接的区域。
Autoradiographic, axonal degeneration, and horseradish peroxidase fiber tracing methods were employed to investigate the organization, development and potential plasticity of the thalamocortical projection to the somatic sensory cortex of the rat. In the adult animal, thalamocortical terminals are concentrated primarily in layers I and IV and in the upper part of layer VI. Fibers terminating in layers IV and VI arise from a different thalamic region than those terminating in layer I. Discrete clusters of fibers and terminals 250–450 μm wide are distributed only to the parts of the SI cortex containing dense aggregates of layer IV granule cells and not to the intervening, less granular and commissurally connected zones.