Limitations of single-channel EEG on the forehead for neonatal seizure detection
Limitations of single-channel EEG on the forehead for neonatal seizure detection
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DOI：
10.1038/jp.2008.195
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发表时间：
2009-03-01
影响因子：
2.9
通讯作者：
Clancy, R. R.
中科院分区：
文献类型：
--
作者：
Wusthoff, C. J.;Shellhaas, R. A.;Clancy, R. R.
目的：在波幅积分脑电图中，导联放置在前额是方便的，但这个位置对新生儿癫痫发作（NS）检测灵敏度的影响尚不清楚。本研究描述了单一脑电图通道检测神经网络的局限性。研究设计：记录取自具有NS的传统脑电图（CEEGs）的数字库，先前表征为双中心通道，C(3) -> C(4)。我们分析了单个前额通道Fp(3) -> Fp(4)的电图特征。结果：共包括125个脑电图的330次癫痫发作。使用Fp(3) -> Fp(4)， 66%的记录中至少检测到一个NS，而使用C(3) -> C(4)， 90%的记录中检测到NS （P < 0.0001）。在330例癫痫发作中，46%出现在Fp(3) -> Fp(4)中，73%出现在C(3) -> C(4)中（P < 0.0001）。Fp(3) -> Fp(4)组比C(3) -> C(4)组（P < 0.006）和CEEG组（P < 0.0001）发作时间短。结论：单前额通道比双中心通道或脑电图更难检测到神经性脑炎。在Fp(3) -> Fp(4)中，三分之一的癫痫发作记录被遗漏，超过一半的癫痫发作未被发现。
Objectives: In amplitude-integrated EEG, lead placement across the forehead is convenient, but this location has unknown effects on neonatal seizure (NS) detection sensitivity. This study describes the limits of NS detection by a single forehead EEG channel.Study Design: Records were taken from a digital library of conventional EEGs (CEEGs) with NS, previously characterized at a bicentral channel, C(3) -> C(4). We analyzed electrographic characteristics in a single forehead channel, Fp(3) -> Fp(4).Result: A total of 330 seizures from 125 CEEGs were included. With Fp(3) -> Fp(4) at least one NS was detected in 66% of records vs 90% using C(3) -> C(4) (P < 0.0001). Of 330 seizures, 46% appeared in Fp(3) -> Fp(4) vs 73% in C(3) -> C(4) (P < 0.0001). Seizures appeared briefer in Fp(3) -> Fp(4) than C(3) -> C(4) (P < 0.006) and CEEG (P < 0.0001).Conclusion: NSs are significantly more difficult to detect with a single forehead channel than bicentrally or on CEEG. In Fp(3) -> Fp(4), a third of records with seizures were missed and over half of seizures were undetected.