HEART-RATE VARIABILITY ANALYSIS IN FULL-TERM INFANTS - SPECTRAL INDEXES FOR STUDY OF NEONATAL CARDIORESPIRATORY CONTROL
HEART-RATE VARIABILITY ANALYSIS IN FULL-TERM INFANTS - SPECTRAL INDEXES FOR STUDY OF NEONATAL CARDIORESPIRATORY CONTROL
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DOI：
10.1203/00006450-198909000-00004
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发表时间：
1989-09-01
影响因子：
3.6
通讯作者：
GIDDENS, DP
中科院分区：
文献类型：
--
作者：
BALDZER, K;DYKES, FD;GIDDENS, DP
本文研究了20例出生后30 ~ 60 h的健康足月婴儿在安静睡眠时的心率和呼吸，目的是确定代表正常新生儿心率变异性（HRV）特征的频谱指数。总HRV功率和功率在不同频带上的分布在婴儿中差异很大。对测量变量的聚类分析表明，人群分为两组，表现出明显不同的HRV行为模式。其中一组（11例）患儿呼吸频率较低，呼吸频率（呼吸性窦性心律失常（RSA）频带）>总功率（TP）的20%时HRV功率较低。低频频段功率与RSA频段功率之比< 4。另一组新生儿（9例）呼吸频率较高，RSA功率<总功率的20%，频率与RSA功率比较低[4]。低频与TP和RSA与TP图的回归分析有力地支持了HRV行为确实存在两种不同模式的假设。将表面上正常的新生儿分成两组可能部分归因于呼吸频率和呼吸模式的差异。然而，交感和副交感神经系统控制平衡的差异，可能与自主神经成熟有关，也可能导致群体分离。本研究中HRV谱分析的指标对新生儿心肺控制的研究有一定的价值。
The heart rate and respirations of twenty healthy full-term infants between 30 and 60 h postnatal age were studied during quiet sleep with the objective of defining spectral indices which represent normal neonatal heart rate variability (HRV) characteristics. Total HRV power and the distribution of power across different frequency bands varied considerably among infants. Cluster analysis on the measured variables indicated that the population divided into two groups that represented significantly different patterns of HRV behavior. In one group (11 subjects), infants had lower breathing rates and HRV power in a band about the respirtion frequency [respiratory sinus arrhythmia (RSA) band] was more than 20% of the total power (TP). Additionally, the ratio of low frequency band power to RSA band power was < 4. The other group of neonates (nine subjects) had relatively higher breathing rates, RSA power < 20% of total power, and low frequency to RSA power ratio > 4. Regression analysis of low frequency versus TP and RSA versus TP graphs gave strong support to the hypothesis that there were indeed two distinct patterns of HRV behavior. Separation of apparently normal neonates into two groups may be attributed partially to differences in respiratory rates and breathing patterns. However, it is possible that differences in the balance between sympathetic and parasympathetic nervous system control, perhaps related to autonomic maturation, also contribute to group separation. The indices developed from HRV spectral analysis in this investigation may be of value in the study of cardiorespiratory control in neonates.